Results 211 to 220 of about 1,474,638 (301)

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou   +10 more
wiley   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

European Delphi consensus on specific training, implementation requirements, and clinical use for the Hugo™ robotic-assisted surgery platform in colorectal procedures. [PDF]

open access: yesInt J Colorectal Dis
Arroyo A   +11 more
europepmc   +1 more source

PEC‐DFM Hybrid‐Sensor Based on Nanoparticle‐Resolved Estimation for Sensitive and Reversible Glucose Monitoring

open access: yesAdvanced Science, EarlyView.
Abstract The accurate detection of glucose in wound exudate is critically important for monitoring chronic wound healing. While photoelectrochemical (PEC) sensors are widely used, they often suffer from material degradation caused by redox reactions during operation. Herein, we introduce a dark‐field microscopy (DFM) setup integrated with a PEC system,
Zihao Zhang   +7 more
wiley   +1 more source

Early BAL microRNA Signatures Delineate Biological Trajectories Towards CLAD After Lung Transplantation. [PDF]

open access: yesCells
Gaudioso G   +17 more
europepmc   +1 more source

Exotic clustering in Ra-222,Ra-224,Ra-226

open access: yes, 2016
Buck, B, Merchant, A, Perez, S
openaire   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

The Impact of GLP-1 Receptor Agonists on Esophagogastroduodenoscopy Outcomes: A Retrospective Cohort Study in a Predominantly African American Population. [PDF]

open access: yesJGH Open
El Sabagh A   +13 more
europepmc   +1 more source

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