Results 51 to 60 of about 3,384 (210)

A case of disseminated intravascular coagulation following tumour lysis syndrome due to small cell carcinoma of the lung

open access: yesRespirology Case Reports, 2023
A 64‐year‐old man was diagnosed with small cell lung cancer (SCLC) with multiple bone and liver metastases and bone marrow metastases. Spontaneous tumour lysis syndrome (TLS) was observed before starting chemotherapy with carboplatin, etoposide, and ...
Saeko Takahashi   +4 more
doaj   +1 more source

Translatability score revisited: differentiation for distinct disease areas [PDF]

open access: yes, 2017
Background: Translational science supports successful transition of early biomedical research into human applications. In 2009 a translatability score to assess risk and identify strengths and weaknesses of a given project has been designed and ...
Wehling, Martin, Wendler, Alexandra
core   +2 more sources

T‐Cell–Redirecting Immunotherapies in Relapsed/Refractory Mantle Cell Lymphoma: Current Evidence, Sequencing, and Future Directions

open access: yesEuropean Journal of Haematology, Volume 116, Issue 2, Page 129-141, February 2026.
ABSTRACT Relapsed/refractory (R/R) mantle cell lymphoma (MCL) remains a therapeutic challenge, particularly in patients with high‐risk features or prior exposure to Bruton's tyrosine kinase inhibitors (BTKis). The advent of T‐cell–redirecting immunotherapies, including chimeric antigen receptor T‐cell (CAR‐T) therapy and bispecific antibodies (BsAbs ...
Santino Caserta   +10 more
wiley   +1 more source

A double blind placebo controlled randomized trial of the effect of acute uric acid changes on inflammatory markers in humans: A pilot study.

open access: yesPLoS ONE, 2017
Uric acid has been linked with increased risk of chronic disease such as cardiovascular disease and this association has been attributed to a pro-inflammatory effect.
Toshiko Tanaka   +5 more
doaj   +1 more source

اثر راسبوريکيس وآلوپورينول در پيشگيری و درمان بيماران مبتلا به هيپراوريسمی ناشی از سندروم ليز تومور در کودکان مبتلا به لوسمی و لنفوم در بيمارستان کودکان حضرت علی اصغر(ع): مطالعه کوهورت [PDF]

open access: yes, 2010
زمينه و هدف: سندروم ليز تومور عبارت است از آزادی مواد داخل سلولی به درون جريان خون به طور خود بخودی و يا به دنبال درمان ضد سرطان که با هيپراوريسمی، هيپر کالمی، هيپرفسفاتمی و هيپوکلسمی خود را نشان می‌دهد.
ارجمندی رفسنجانی, خدیجه   +2 more
core  

Transient myeloproliferative disorder in a newborn with down syndrome treated with rasburicase for the risk of development of tumor lysis syndrome: A case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Transient myeloproliferative disorder is a hematologic abnormality characterized by an uncontrolled proliferation of myeloblasts in peripheral blood and bone marrow that primarily affects newborns and babies with Down syndrome.
Hatzistilianou Maria   +5 more
doaj   +1 more source

Spontaneous Tumor Lysis Syndrome in Blastoid-Variant Mantle Cell Lymphoma: Considerations for the General Internist

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2020
Spontaneous tumor lysis syndrome (SPTLS) is a rare phenomenon that can manifest in rapidly proliferating hematological malignancies and solid tumors prior to initiating cytotoxic therapy.
Vishal Patel MD, Robert Case MD
doaj   +1 more source

Acute post-streptococcal glomerulonephritis – immune-mediated acute kidney injury – case report and literature review

open access: yesCentral European Journal of Immunology, 2021
Acute post-streptococcal glomerulonephritis (APSGN) is an immunological complication of infection with group A -hemolytic streptococcus (GAS). The disease manifests as microscopic or gross hematuria, arterial hypertension, edema, and acute kidney injury
Piotr Skrzypczyk   +3 more
doaj   +1 more source

The addition of rituximab to fludarabine and cyclophosphamide improves progression-free survival in patients with previously treated chronic lymphocytic leukemia. [PDF]

open access: yes, 2010
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the United States. There has been considerable progress in understanding the biology and treatment of CLL in last 20 years.
Mahipal, Amit, Weiss, Mark
core   +2 more sources

Pharmacogenomic Calling From Whole‐Exome Sequencing in the Taiwanese Population—A Real‐World Experience

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study evaluated pharmacogenomic (PGx) calling from whole‐exome sequencing (WES) in 3562 Taiwanese individuals. Fourteen pharmacogenes were reliably identified, with each person carrying an average of ~2.4 actionable phenotypes. The high actionable frequencies of G6PD deficiency and HLA‐B*58:01 highlight ethnic differences and support WES as a ...
Hsu‐Heng Lin   +9 more
wiley   +1 more source

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