Results 61 to 70 of about 3,384 (210)

Multicentre, prospective, randomised, open-label, blinded end point trial of the efficacy of allopurinol therapy in improving cardiovascular outcomes in patients with ischaemic heart disease: protocol of the ALL-HEART study [PDF]

, 2016
Introduction Ischaemic heart disease (IHD) is one of the most common causes of death in the UK and treatment of patients with IHD costs the National Health System (NHS) billions of pounds each year. Allopurinol is a xanthine oxidase inhibitor used to
ALL-HEART Study Group, Avery, Anthony, Begg, Alan, Ford, Ian, Hawkey, Chris, MacDonald, Thomas M., Mackenzie, Isla S., Struthers, Allan D., Taggar, Jaspal, Walker, Andrew, Wei, Li   +10 more
core   +5 more sources

Lower Neighborhood Socioeconomic Status Is Associated With Intensive Care Unit Admission at Initial Presentation in Children With Acute Leukemia

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Lower socioeconomic status (SES) and minority race and ethnicity are associated with lower overall survival in pediatric leukemia. Higher acuity at initial presentation is associated with mortality during induction chemotherapy. We hypothesized that the mechanism underlying these associations is differences in access to healthcare ...
Chynna M. Swift, Earl Chism, Katherine Lin, Aly Cortella, Tanushree Banerjee, Jacklyn Sanchez Alvarez, Lena E. Winestone   +6 more
wiley   +1 more source

A Phase 2 study of CPX‐351 in combination with venetoclax in patients with newly diagnosed high‐risk acute myeloid leukemia

HemaSphere, Volume 9, Issue 10, October 2025.
Abstract Venetoclax has been combined with intensive chemotherapy regimens in the treatment of acute myeloid leukemia (AML). We aimed to investigate the safety and efficacy of venetoclax combined with full‐dose CPX‐351 (CPX + VEN) in newly diagnosed (ND) AML.
Wei‐Ying Jen, Jennifer Croden, Emmanuel Almanza‐Huante, Courtney DiNardo, Kelly Chien, Danielle Hammond, Wei Qiao, Yesid Alvarado, Lucia Masarova, Andres E. Quesada, Sherry Pierce, Alex Bataller, Guillermo Garcia‐Manero, Amin Alousi, Nicholas Short, Naval Daver, Farhad Ravandi, Hagop Kantarjian, Tapan M. Kadia   +18 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase deficiency presenting with rhabdomyolysis in a patient with coronavirus disease 2019 pneumonia: a case report

Journal of Medical Case Reports, 2022
Background Glucose-6-phosphate dehydrogenase deficiency is a rarely recognized predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during the pandemic.
Regina Yu, Chien-Rong Chen, Darci Evans, Xin Qing, Moran Gotesman, Gangadarshni Chandramohan, Thomas Kallay, Henry J. Lin, Tiffany P. Pedigo   +8 more
doaj   +1 more source

Real World Analysis of G6PD Testing Prior to the Use of Rasburicase in Hematologic Malignancies; A Single Center Experience [PDF]

, 2023
Radhika Kulkarni, Oscar Hinojosa, Vijayalakshmi Donthireddy   +2 more
openalex   +1 more source

HIV-associated multi-centric Castleman’s disease with multiple organ failure: cuccessful treatment with rituximab [PDF]

, 2010
Introduction: Multicentric Castleman's Disease (MCD), a lymphoproliferative disorder associated with Human Herpes Virus-8 (HHV-8) infection, is increasing in incidence amongst HIV patients.
Agarwal, B, Cleverley, JR, Cwynarski, K, Doyle, T, Isaacson, PG, Johns, RH, Lipman, M, Shaw, S   +7 more
core  

Adverse drug events in a paediatric intensive care unit: a prospective cohort [PDF]

, 2013
Objectives: To describe adverse drug events (ADEs) in children under intensive care, identify risk factors and tools that can detect ADEs early, and the impact on length of stay (LOS).Design: A prospective observational study.Setting: Paediatric ...
Alonso, Carolina F. R., Araujo, Orlei Ribeiro, Arduini, Rodrigo G., Shibata, Audrey R. O., Silva, Dafne C. B., Troster, Eduardo J.   +5 more
core   +2 more sources

Complications at Diagnosis of Pediatric Chronic Myeloid Leukemia in Chronic Phase

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Chronic myeloid leukemia (CML) is uncommon during the first two decades of life, resulting in limited experience of pediatricians in handling this leukemia. This is even more true when it comes to managing rare complications at the time of diagnosis.
Nirmalya Roy Moulik, Uma Athale, Markus Metzler, Frederic Millot, Meinolf Suttorp   +4 more
wiley   +1 more source

Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma

Case Reports in Critical Care, 2023
Type B lactic acidosis is an uncommon medical emergency in which acid production overwhelms hepatic clearance. This specific etiology of lactic acidosis occurs without organ hypoperfusion and has been most commonly described in patients with hematologic ...
Ikemsinachi C. Nzenwa, Margaret Berquist, Toby J. Brenner, Aida Ansari, Hamid D. Al-Fadhl, Michael Aboukhaled, Shivani S. Patel, Ethan E. Peck, Mahmoud D. Al-Fadhl, Anthony V. Thomas, Nuha Zackariya, Mark M. Walsh, Jose A. Bufill   +12 more
doaj   +1 more source

Navigating Rare Presentations: Recurrent Burkitt Lymphoma Presenting as a Jejunal Mass

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Burkitt lymphoma (BL) is an aggressive B‐cell malignancy characterized by rapid progression and MYC gene translocations. Jejunal involvement in BL is rare compared to more common sites like the lymph nodes and central nervous system. Diagnosing BL in the jejunum is particularly challenging as it can mimic other gastrointestinal conditions ...
Tejas Nikumbh, Archit Garg, Himani Mongia, Tushar Abhinav, Nivesh Yadav, Udit Asija, Jialing Huang, Danial Nadeem, Kishore Kumar, Amit Sohagia   +9 more
wiley   +1 more source