Results 71 to 80 of about 3,384 (210)

Potential cost savings with implementation of systemwide Rasburicase protocol [PDF]

open access: yes, 2022
Purpose: Tumor Lysis Syndrome is a condition that takes place when apoptosis in cancer cells occurs within a short time period. This condition can lead to organ dysfunction and even death.
Gundersen, Parker, Lee, Adalyn
core   +1 more source

Navigating Pharmacogenomic Testing in Practice: Who to Test and When to Test

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 3, Page 561-566, September 2025.
There is increasing attention on the clinical utility and value of pharmacogenetic (PGx) testing to individualize medication management. Most clinical practice guidelines from medical professional societies do not recommend routine PGx testing, with a few key exceptions.
James M. Stevenson   +4 more
wiley   +1 more source

Tumor lysis syndrome following cabazitaxel administration for metastatic castration‐resistant prostate cancer: A case report

open access: yesIJU Case Reports, 2019
Introduction Tumor lysis syndrome is a rare and potentially fatal complication of oncological treatment. It is characterized by biochemical changes associated with the rapid lysis of malignant cells, usually after chemotherapy.
Masashi Oshima   +7 more
doaj   +1 more source

A rare case of spontaneous tumor lysis syndrome in multiple myeloma

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2020
Spontaneous tumor lysis syndrome is an uncommon oncologic emergency. It occurs when a massive number of malignant cells release their contents to the blood stream without previous cancer treatment. TLS carries a mortality rate exceeding 15%.
Louay Aldabain   +2 more
doaj   +1 more source

Economic purification of recombinant uricase by artificial oil bodies

open access: yesBioresources and Bioprocessing, 2022
Rasburicase is an expensive treatment used to control hyperuricemia caused by tumour lysis syndrome (TLS). In this study, a non-chromatographic method was designed based on nano-oil bodies for convenient and economical purification of the recombinant ...
Fatemeh Saadat   +3 more
doaj   +1 more source

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation. [PDF]

open access: yes, 2015
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by
Busso, N.   +8 more
core   +1 more source

Outcomes for Patients With Myeloid Neoplasms Treated With Chemotherapy Plus Venetoclax After Prior Venetoclax Therapy

open access: yeseJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT Background Outcomes for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that have progression after treatment with hypomethylating agent (HMA) and venetoclax (VEN) are poor. However, data for chemotherapy and VEN (C+VEN) therapy after prior treatment with HMA+VEN are limited.
Rafael Madero‐Marroquin   +14 more
wiley   +1 more source

Tumor lysis syndrome in gynecologic cancers: An uncommon but important diagnosis to recognize

open access: yesGynecologic Oncology Reports, 2019
Objectives: To describe the incidence, treatment and outcomes associated with tumor lysis syndrome (TLS) in women with gynecologic cancer (GOC). Methods: A retrospective multi-institutional review of TLS associated with GOC.
T. Castellano   +3 more
doaj   +1 more source

A Rare Oncologic Emergency: Spontaneous Tumor Lysis Syndrome in Metastatic Colon Adenocarcinoma [PDF]

open access: yes, 2019
Tumor lysis syndrome is an oncologic emergency that can present with variable symptoms and is truly a laboratory-based diagnosis without pathognomonic clinical findings.
Daniel, Nicholas J.   +3 more
core  

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