Results 81 to 90 of about 3,384 (210)

Integrated Phenotypic and Genotypic Approaches for Accurate Diagnosis of G6PD Deficiency: Implications for Drug Safety in Thailand

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency holds critical health concerns, particularly due to its association with drug‐induced hemolysis triggered by medications such as antimalarials. This condition poses significant risks in malaria‐endemic regions where the prevalence and genetic diversity of G6PD deficiency further complicate ...
Natnicha Pengsuk, Kamonwan Chamchoy, Chatnapa Duangdee, Jantawan Satayarak, Naowarat Saralamba, Wang Nguitragool, Usa Boonyuen   +6 more
wiley   +1 more source

Tumor lysis syndrome and mediastinal mass

Journal of Pediatric Critical Care
Tumor lysis syndrome is triggered by rapid malignant cell destruction following chemotherapy, immunotherapy, or radiation and is usually seen in leukemias and lymphomas.
Sathishkumar Kandath, Vinitha Krishnan Anirudhan   +1 more
doaj   +1 more source

Rasburicase

Reactions Weekly, 2006
europepmc   +2 more sources

Frequency and Implications of High‐Risk Pharmacogenomic Phenotypes Identified in a Diverse Australian Pediatric Oncology Cohort

Clinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Pharmacogenomics remains underutilized in pediatric oncology, despite the existence of evidence‐based guidelines. Implementation of pharmacogenomics‐informed prescribing could improve medication safety and efficacy in pediatric oncology patients, who are at high risk of adverse drug reactions.
Claire Moore, Andreas Halman, Tayla Stenta, Dhrita Khatri, Elizabeth Williams, Roxanne Dyas, Julian Stolper, David A. Elliott, Rachel Conyers   +8 more
wiley   +1 more source

Urate-Lowering Agents in Asymptomatic Hyperuricemia: Role of Urine Sediment Analysis and Musculoskeletal Ultrasound

Kidney & Blood Pressure Research, 2018
Current urate-lowering therapy (ULT) includes three direct acting drugs (allopurinol, febuxostat, Rasburicase) and at least four ‘indirect’ drugs with other important targets (canagliflozin, losartan, fenofibrate and sevelamer).
Davide Viggiano, Giuseppe Gigliotti, Gianfranco Vallone, Anna Giammarino, Michelangelo Nigro, Giovambattista Capasso   +5 more
doaj   +1 more source

Acute renal failure in patients with tumour lysis sindrome [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2016
Hematologic malignancies (leukemia, lymphoma, multiple myeloma, et al.), as well as solid tumours (renal, liver, lung, ovarian, etc.), can lead to acute or chronic renal failure.
Poskurica Mileta, Petrović Dejan, Poskurica Mina   +2 more
doaj   +1 more source

Children's Oncology Group's 2013 blueprint for research: Non‐Hodgkin lymphoma [PDF]

, 2013
Non‐Hodgkin lymphomas account for approximately 7% of cancers diagnosed in patients less than 20 years of age, with approximately 800 cases diagnosed annually at COG institutions.
Bollard, Catherine M., Gross, Thomas G., Lim, Megan S.   +2 more
core   +1 more source

Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for G6PD deficiency

Tropical Medicine &International Health, Volume 30, Issue 5, Page 437-457, May 2025.
Abstract Accurate diagnosis of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is crucial for relapse malaria treatment using 8‐aminoquinolines (primaquine and tafenoquine), which can trigger haemolytic anaemia in G6PD‐deficient individuals. This is particularly important in regions where the prevalence of G6PD deficiency exceeds 3%–5%, including ...
Usa Boonyuen, Beatriz Aira C. Jacob, Kamonwan Chamchoy, Natnicha Pengsuk, Sirinyatorn Talukam, Chanya Petcharat, Emily R. Adams, Thomas Edwards, Kobporn Boonnak, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis   +11 more
wiley   +1 more source

Spontaneous Tumor Lysis Syndrome

Journal of Investigative Medicine High Impact Case Reports, 2015
Tumor lysis syndrome (TLS) is a known complication of malignancy and its treatment. The incidence varies on malignancy type, but is most common with hematologic neoplasms during cytotoxic treatment. Spontaneous TLS is thought to be rare.
Alicia C. Weeks MD, Michelle E. Kimple PhD   +1 more
doaj   +1 more source

RASBURICASE-INDUCED HYPOXIA: METHEMOGLOBINEMIA IN NORMAL G6PD ACTIVITY [PDF]

, 2023
J. Bahgat
openalex   +1 more source