Results 131 to 140 of about 3,197 (223)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Fotballspilleres opplevelse av rasisme

, 2022
Formålet med denne studien er å undersøke hvilke opplevelser fotballspillere har med rasisme og hvordan de føler dette kan gå ut over deres arbeidshverdag. Dette er en kvalitativ studie hvor datainnsamlingen foregikk gjennom semi-strukturerte dybdeintervju av fem profesjonelle fotballspillere.
openaire   +1 more source

Cultural Diversity A Glimpse Over the Current Debate in Sweden [PDF]

A year and a half ago, the Swedish government decided 2006 to be The Year for Cultural Diversity (Agenda för Mångkultur, 2005). The general purpose, according to the directive, is to facilitate the possibilities for all citizens to participate in all ...
Kiflemariam Hamde
core  

”Mångkulturalitet” Begreppets uppfattning och dess påverkan i vardagsarbetet i skolan. [PDF]

, 2009
Barnens bakgrund och erfarenheter spelar en viktig roll i deras utvecklingsprocess. Enligt läroplanen är det skolans uppgift att ge barnet god stimulans för dess livslånga lärande.
Aguilar, Nadia, Farester, Kevin
core  

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Stigmatisering och rasism i det svenska migrationssamtalet och det diasporiska motståndet

Sociologisk Forskning, 2017
Khalid Khayati
doaj   +1 more source

Rasism i skolan : Hur lärare arbetar för att motverka rasism

, 2010
The purpose of this paper is to show how practicing teachers work to prevent racism. Based on four interviews with teachers at low-, middle- and high schools, where these schools differ in numbers of immigrants and geographical location. Conclusion: None of the four teachers feel that racism is a problem at their school; however, they are confident ...
openaire   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

A Reactive Antagonist Strategy: Cysteine‐Directed Covalent Molecular Glue in Plant Hormone Receptor Regulation

Advanced Science, EarlyView.
The plant hormone jasmonate is perceived by COI1‐JAZ co‐receptors comprising a single F‐box protein COI1 and multiple JAZ repressors with overlapping functions, complicating genetic analysis. We present a reactive antagonist (RA) strategy that selectively promotes COI1 binding to a cysteine‐engineered JAZ variant while blocking wild‐type JAZs, enabling
Minoru Ueda, Kotaro Matsumoto, Takao Nomura, Yousuke Takaoka, Taichi Okumura, Wataru Kozaki, Hikaru Hoshikawa, Yuho Nishizato, Andrea Chini, Roberto Solano, Katsumi Maenaka   +10 more
wiley   +1 more source

Feminism eller rasism? En kritisk läsning av den svanske hedersmordsdebatten

Kvinder, Køn & Forskning, 2002
Anna Bredström
doaj   +1 more source