Results 41 to 50 of about 3,197 (223)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

KONSTRUKTIONEN AV ETNICITET - En kvalitativ studie om hur lärare och studerande upplever etnicitetsperspektivet på socionomprogrammet vid Göteborgs universitet [PDF]

open access: yes, 2008
The primary purpose of this essay is to study and describe how the concept of “ethnicity” is introduced, defined and constructed at the Universities of Social Work Education through the perspectives of students attending and teachers/researchers ...
Rebwar, Ala   +2 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Rasism i seminarierummet: Strategisk empati och de svåra känslornas pedagogik

open access: yesHögre Utbildning
Denna text tar sin utgångspunkt i två undervisningssituationer där studenter formulerade rasistiska synsätt. Undervisningen ägde rum på ett internationellt mastersprogram.
Magnus Rodell
doaj   +1 more source

Kulturell kompetens och bemötande i arbete med invandrarfamiljer : Inom det sociala området och vårdarbetet [PDF]

open access: yes, 2017
Examensarbetet är en del av beställningsarbetet Resursstarka barn – mångkulturell vård och omsorg bland barn och familjer, som yrkeshögskolan Novia har tagit emot. Syftet med examensarbetet är att utreda vad kulturell kompetens och bemötande innebär inom
Andersson, Synnöve   +2 more
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Rollspel som arbetsmetod i ungdomsverksamheten [PDF]

open access: yes, 2011
Studien gjordes som ett beställningsarbete till Finlands Röda Kors, Österbottens svenska distrikt. I studien kommer jag kort att berätta om Röda Korset och om rollspel, samt sedan fördjupar mig i samarbets-/ ungdomsprojektet På Flykt som genomfördes i ...
Valkeakari, Lena
core  

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