Results 51 to 60 of about 3,229 (224)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
KONSTRUKTIONEN AV ETNICITET - En kvalitativ studie om hur lärare och studerande upplever etnicitetsperspektivet på socionomprogrammet vid Göteborgs universitet [PDF]
The primary purpose of this essay is to study and describe how the concept of “ethnicity” is introduced, defined and constructed at the Universities of Social Work Education through the perspectives of students attending and teachers/researchers ...
Rebwar, Ala +2 more
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Ryssar och estländare i finlandssvensk press : de berövar oss, tjänar oss och behöver vår hjälp [PDF]
Peer ...
Haavisto, Camilla
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Att tårta en politiker – Hot mot demokratin eller bara lite vaniljvisp i örat? [PDF]
Title: Att tårta en politiker - hot mot demokratin eller bara lite vaniljvisp i örat? Number of pages: 35 Authors: Maja Larsson & Josefin Wetterberg Tutor: Marina Ghersetti Course: Journalistikgranskning Period: Fall 2013 University: University of ...
Larsson, Maja, Wetterberg, Josefin
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Young people's attitudes towards Muslims in Sweden [PDF]
Since the 1950's, the Muslim population in Sweden has grown from just a few individuals to approximately 350,000 of which one third is of school age or younger. With the use of multiple regression technique, the principal objective of this study has been
Bevelander, Pieter, Otterbeck, Jonas
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

