Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Under extrem press En kvantitativ studie av hur svensk dagspress förhåller sig till politisk extremism [PDF]
, 2014 Authors: Martin Mederyd Hårdh, Frida Nygren, Daniel Paulsson Title: Under Extreme Pressure Level: Bachelor of Journalism Location: University of Gothenburg Language: Swedish Method: Quantitative content analysis Pages: 38 Politically motivated ...
Mederyd Hård, Martin +2 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Det diskursiva skapandet av en nation och en främling. En kritisk diskursanalys av hur Lifos rapport diskursivt skapar bilden av den somaliska kvinnan och en svensk jämställdhet. [PDF]
, 2016 In this essay I perform a critical discourse analysis of a report on the situation of Somali women by Lifos, the Swedish Migration Boards Country of Origin Information system.
Larsson, Felix
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
"Synsvinkler på den danske Straffelov § 266 b", "Aspects on the Danish Penal Code § 266 b" [PDF]
, 2007 Resumé Der er en løbende konflikt mellem ytringsfrihed og racistiske krænkelser i dagens samfund. I Danmark er der en del nationale såvel som internationale forpligtelser, som indebærer at samfundet skal bekæmpe racismen, hvilket nødvendiggør ...
Bernes, Anna-Synnöve
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Att tårta en politiker – Hot mot demokratin eller bara lite vaniljvisp i örat? [PDF]
, 2014 Title: Att tårta en politiker - hot mot demokratin eller bara lite vaniljvisp i örat? Number of pages: 35 Authors: Maja Larsson & Josefin Wetterberg Tutor: Marina Ghersetti Course: Journalistikgranskning Period: Fall 2013 University: University of ...
Larsson, Maja, Wetterberg, Josefin
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Från Bagdad till Nossebro – En granskning av flyktingintroduktionen i Essunga kommun [PDF]
, 2008 Flyktingmottagningen i Essunga kommun är relativt nystartad och de första flyktingarna flyttade dit under hösten 2006. Det övergripande syftet med vår uppsats är att granska hur introduktionen av flyktingar i Essunga kommun med centralorten Nossebro har ...
Clausson, Rebecca, Söderberg, Erika
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