Results 181 to 190 of about 3,207,063 (305)

Simultaneous Determination of Fexinidazole and Its Major Metabolites in Rat Plasma by UPLC-MS/MS: Method Validation and Application to Pharmacokinetic Study. [PDF]

Drug Des Devel Ther
Qian C, Jiang S, Fu H, Shen Y, Zhan R, Lan X, Zhou C.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Interdisciplinary Approach at the Border Between Hematology and Cardiology

Journal of Interdisciplinary Medicine, 2017
Opincariu Diana, Rat Nora
doaj   +1 more source

The effect of non-tobacco nicotine on bone healing: a systematic review and application to total joint arthroplasty. [PDF]

J Orthop Surg Res
Travis LM, Cacciatore JC, Schuster JA, Khan F, Stern JM, Moore MR, Hneiny L, Hernandez VH, McNamara CA.   +8 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multitissue, multi-time point transcriptomic atlas of aging in mice and rats. [PDF]

Sci Adv
Shavlakadze T, Xiong K, Donne R, McEwen C, Gadi A, Wakai M, Salmon H, Treinish J, Pavlopoulos E, Proctor L, Li S, Negron N, Ni M, Wei Y, Bai Y, Glass DJ.   +15 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Functional xenogeneic hematopoietic cells maintaining donor-dominant identity and immune tolerance enable therapy. [PDF]

Exp Hematol Oncol
Xiong S, Zhou R, Wei C, Wang X, Tang Y, Dong L, Yu P, Pei D, Chen Z, Chen SJ, Cheng L.   +10 more
europepmc   +1 more source

Falklandski rat kao rat distrakcije

Rat iz 1982. godine, odnosno Falklandski rat, izvrstan je primjer koncepta distrakcijskog rata, u kojem vlade koriste vanjske vojne sukobe kako bi skrenule pažnju javnosti s unutarnjih problema. Argentinska vojna diktatura, suočena s ekonomskom krizom i političkom nestabilnošću, pokrenula je invaziju na Falklandske otoke kako bi mobilizirala nacionalni
openaire   +2 more sources