Results 31 to 40 of about 307,599 (226)

Binary Social Mimic Optimization Algorithm With X-Shaped Transfer Function for Feature Selection

IEEE Access, 2020
Definitive optimization algorithms are not able to solve high dimensional optimization problems when the search space grows exponentially with the problem size, and an exhaustive search also becomes impractical. To encounter this problem, researchers use
Kushal Kanti Ghosh, Pawan Kumar Singh, Junhee Hong, Zong Woo Geem, Ram Sarkar   +4 more
doaj   +1 more source

Discontinuous Galerkin approximations in computational mechanics: hybridization, exact geometry and degree adaptivity [PDF]

, 2019
Discontinuous Galerkin (DG) discretizations with exact representation of the geometry and local polynomial degree adaptivity are revisited. Hybridization techniques are employed to reduce the computational cost of DG approximations and devise the ...
Giacomini, Matteo, Sevilla Cárdenas, Rubén   +1 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Accurate Approximation of ZF Massive MIMO Channel Rate With a Finite Antenna Over Ricean Fading Channel

IEEE Access, 2018
In a typical downlink massive multiple-input and multiple-output (massive MIMO) system, the available degree of freedom (DoF) and multiplexing gain improve the channel rate.
James Kweku Nkrumah Nyarko, Jian Xie, Rugui Yao, Yuexian Wang, Ling Wang   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Cooperation driven by mutations in multi-person Prisoner's Dilemma

, 2004
The n-person Prisoner's Dilemma is a widely used model for populations where individuals interact in groups. The evolutionary stability of populations has been analysed in the literature for the case where mutations in the population may be considered as
Adachi, Akimov, Albin, Anders Eriksson, Axelrod, Axelrod, Boyd, Eigen, Eigen, Flood, Hardin, Hauert, Kristian Lindgren, Lindgren, Lindgren, Lindgren, Matsushima, Maynard Smith, Miller, Molander, Molander, Nowak, Nowak, Nowak, Rapoport, Rice, Schelling, Schuster, Sugden   +28 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

On the improved convergence of lifted distributional Gauss curvature from Regge elements

Results in Applied Mathematics
Although Regge finite element functions are not continuous, useful generalizations of nonlinear derivatives like the curvature, can be defined using them.
Jay Gopalakrishnan, Michael Neunteufel, Joachim Schöberl, Max Wardetzky   +3 more
doaj   +1 more source