Results 121 to 130 of about 489,800 (291)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Corporate ESG performance, digital transformation and climate risk disclosure
Sustainable FuturesThis paper uses the data of all listed companies in China's A-share market from 2010 to 2022, and employs textual analysis to construct climate risk disclosure indicators using corporate annual reports to validate the relationship between ESG ratings and
Yufei Yan, Changhao Gong, Hua Zhang
doaj +1 more source
The Financial Crisis and the Regulation of Credit Rating Agencies: A European Banking Perspective [PDF]
Credit rating agencies (CRAs) bear some responsibility for the financial crisis that started in 2007 and remains ongoing. This is acknowledged by policymakers, market participants, and by the agencies themselves.
Utzig, Siegfried
core +1 more source
Penilaian Kriteria Penarafan Sukuk Di Rating Agency Malaysia (RAM) [PDF]
, 2017 Pertumbuhan signifikan dalam pasaran modal Islam (PMI) didorong oleh kewujudan sukuk sebagai platform untuk mendapatkan dana dalam aktiviti pelaburan.
Abdullah, Norhayati
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Sovereign Rating News and Financial Markets Spillovers: Evidence from the European Debt Crisis [PDF]
This paper examines the spillover effects of sovereign rating news on European financial markets during the period 2007-2010. Our main finding is that sovereign rating downgrades have statistically and economically significant spillover effects both ...
Amadou Sy +2 more
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
ADJUSTED GROSS REVENUE PILOT INSURANCE PROGRAM: RATING PROCEDURE (REPORT PREPARED FOR THE RISK MANAGEMENT AGENCY BOARD OF DIRECTORS) [PDF]
The focus of this paper is on outlining the procedures used to estimate the premium rates for the Adjusted Gross Revenue (AGR) insurance plan. The AGR rating procedures draw substantially on rating procedures used in products currently reinsured and ...
Black, J. Roy
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
How the proposd Basel Guidelines on rating-agency assessments would affect developing countries [PDF]
Using historical data on sovereign and individual borrowers, the authors assess the potential impact on non-high-income countries of linking capital asset requirements for banks to private sector ratings, as the Basel committee has proposed.
Ferri, Giovanni +2 more
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