Results 121 to 130 of about 60,078 (296)

When AAA Means B: The State of Credit Rating in India [PDF]

open access: yes
As in many other countries, India five year old credit rating industry has grown rapidly amidst persistent doubts about the quality of the rating service. This paper evaluates the ratings given by India leading credit rating agency, CRISIL.
Varma, Jayanth R., Ragunathan V
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

CREDIT RATING AGENCIES AND THEIR POTENTIAL IMPACT ON DEVELOPING COUNTRIES [PDF]

open access: yes
Credit rating agencies (CRAs) play a key role in financial markets by helping to reduce the informative asymmetry between lenders and investors, on one side, and issuers on the other side, about the creditworthiness of companies or countries.
Marwan Elkhoury
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

A Monopolistic Credit Rating Agency [PDF]

open access: yes
The paper analyses the demand for credit rating services of a continuum of firms. The firms differ in the probability of their investment's success which is private information.
Anette Boom
core  

Moody’s credit ratings and the stock market performance of Portuguese rated firms [PDF]

open access: yes
Never has the issue of sovereign credit ratings attracted such an interest by policy and opinion makers, bankers and journalists, or even the public opinion, as witnessed in the last couple of years.
Pacheco, Luís
core   +1 more source

Credit Rating Agency Reform Act of 2006 [PDF]

open access: yes, 2006
The report discusses the Credit Rating Agency Reform Act of 2006, that was enacted to correct the perceived problems created by the absence of statutory regulation of credit rating ...
Seitzinger, Michael V.
core  

THE EFFECT OF PROFITABILITY, LIQUIDITY, LEVERAGE AND FIRM SIZE TOWARD BOND RATING ON NON FINANCIAL INSTITUTION LISTED IN INDONESIA STOCK EXCHANGE PERIOD 2010-2014

open access: yesJurnal Riset Manajemen Sains Indonesia, 2015
The Purpose of this research is to know the effects of profitability, liquidity, leverage, and firm size toward bond rating. This research used logistic regression as a method of data analysis.
Umi Mardiyati   +2 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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