Results 121 to 130 of about 34,945,907 (346)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Optical-OFDM VLC System: Peak-to-Average Power Ratio Enhancement and Performance Evaluation

open access: yesSensors
Visible Light Communication (VLC) systems are favoured for numerous applications due to their extensive bandwidth and resilience to electromagnetic interference.
Yasser A. Zenhom   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System

open access: yesMediators of Inflammation, 2016
Background. Dyslipidemia and diabetes are two of the most well established risk factors for the development of cardiovascular disease (CVD). Both of them usually activate a complex range of pathogenic pathways leading to organ damage.
Barbara Toffoli   +4 more
doaj   +1 more source

Effect of obesity on autonomic nervous system [PDF]

open access: yes, 2011
The present study was carried out on 100 volunteers of which 50 subjects with BMI > 30kg/m2 were included in study group and 50 subjects with BMI < 30kg/m2 (non obese) were included in control group.
Simran Grewal, Vidushi Gupta, Int J Cur Bio Med Sci.
core  

Quantum Phase Transition, O(3) Universality Class and Phase Diagram of Spin-1/2 Heisenberg Antiferromagnet on Distorted Honeycomb Lattice: A Tensor Renormalization Group Study

open access: yes, 2010
The spin-1/2 Heisenberg antiferromagnet on the distorted honeycomb (DHC) lattice is studied by means of the tensor renormalization group method. It is unveiled that the system has a quantum phase transition of second-order between the gapped quantum ...
Gang Su   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sex Ratio and the ABO Blood Group System [PDF]

open access: yesJournal of Epidemiology & Community Health, 1954
An interesting association between the sex ratio at birth and the ABO blood group system has been demonstrated by Sanghvi (1951). He showed, in each of two population samples, one from New York and the other from Bombay, that the sex ratio (percentage of males) of Group O infants of Group O mothers was significantly higher than that of Group A infants ...
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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