Results 251 to 260 of about 1,206,877 (302)
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Rational Design Strategies for Nanozymes
ACS Nano, 2023Nanozymes constitute an emerging class of nanomaterials with enzyme-like characteristics. Over the past 15 years, more than 1200 nanozymes have been developed, and they have demonstrated promising potentials in broad applications. With the diversification and complexity of its applications, traditional empirical and trial-and-error design strategies no
Zhen Chen +3 more
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European Journal of Pharmacology, 2009
In this article, current knowledge of drug design is reviewed and an approach of rational drug design is presented. The process of drug development is challenging, expensive, and time consuming, although this process has been accelerated due to the development of computational tools and methodologies.
Soma, Mandal +2 more
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In this article, current knowledge of drug design is reviewed and an approach of rational drug design is presented. The process of drug development is challenging, expensive, and time consuming, although this process has been accelerated due to the development of computational tools and methodologies.
Soma, Mandal +2 more
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Rational Design of Porous Titanophosphates
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Christian, Serre +2 more
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Rational Design of Diamond Electrodes
Accounts of Chemical Research, 2022Diamond electrodes stepped onto the stage in the early 1990s for electroanalytical applications. They possess the features of long-term chemical inertness, wide potential windows, low and stable background currents, high microstructural stability at different potentials and in different media, varied activity toward different electroactive species ...
Nianjun Yang, Xin Jiang
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Rational Design of Electrochemiluminescent Devices
Accounts of Chemical Research, 2021Electrochemiluminescence (ECL) is a light-emitting process which combines the intriguing merits of both electrochemical and chemiluminescent methods. It is an extensively used method especially in clinical analysis and biological research due to its high sensitivity, wide dynamic range, and good reliability. ECL devices are critical for the development
Xiangui Ma +7 more
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International Journal of Computational Models and Algorithms in Medicine, 2014
For the past three decades rationale drug design (RDD) has been developing as an innovative, rapid and successful way to discover new drug candidates. Many strategies have been followed and several targets with diverse structures and different biological roles have been investigated. Despite the variety of computational tools available, one can broadly
Khaled H. Barakat +3 more
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For the past three decades rationale drug design (RDD) has been developing as an innovative, rapid and successful way to discover new drug candidates. Many strategies have been followed and several targets with diverse structures and different biological roles have been investigated. Despite the variety of computational tools available, one can broadly
Khaled H. Barakat +3 more
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2022
This chapter examines how the techniques of rational work design can be traced back to the Second Industrial Revolution and the beginnings of the factory system. Indeed, industrialists such as Frederick Taylor and Henry Ford are most closely associated with the early days of rational work design.
Daniel King, Scott Lawley
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This chapter examines how the techniques of rational work design can be traced back to the Second Industrial Revolution and the beginnings of the factory system. Indeed, industrialists such as Frederick Taylor and Henry Ford are most closely associated with the early days of rational work design.
Daniel King, Scott Lawley
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Aircraft Engineering and Aerospace Technology, 1933
BEFORE examining possible means of improving the performance of aeroplanes, a brief résumé of what has been achieved in this direction since the war is useful, as it helps to indicate the standpoint from which designers generally have approached the problem.
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BEFORE examining possible means of improving the performance of aeroplanes, a brief résumé of what has been achieved in this direction since the war is useful, as it helps to indicate the standpoint from which designers generally have approached the problem.
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Rationally designed DNA-based nanocarriers
Advanced Drug Delivery Reviews, 2019Nanomaterials employed for enhanced drug delivery and therapeutic effects have been extensively investigated in the past decade. The outcome of current anticancer treatments based on conventional nanoparticles is suboptimal, due to the lack of biocompatibility, the deficient tumor targeting, the limited drug accumulation in the diseased region, etc ...
Qiao, Jiang +5 more
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Rationally Designed Multitarget Anticancer Agents
Current Medicinal Chemistry, 2013Balanced modulation of multiple targets is an attractive therapeutic strategy in treating complex diseases including cancer. Comparing with drugs combination, single molecule modulating desirable multiple targets has advantages in pharmacokinetic and pharmacodynamics.
Zhuo, Chen +4 more
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