Results 1 to 10 of about 269,742 (193)
A risk based assessment approach for chemical mixtures from wastewater treatment plant effluents
Environment International, 2022 In this study, 56 effluent samples from 52 European wastewater treatment plants (WWTPs) were investigated for the occurrence of 499 emerging chemicals (ECs) and their associated potential risks to the environment.
Saskia Finckh +11 more
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Cybernetics and Directed Evolution
Кібернетика та комп'ютерні технології, 2023 Results. The place and role of cybernetics methods for solving the global problem of directed evolution are considered. The author investigates the eventual phenomenon of the interaction of two coryphaei of Ukrainian science V.I.
Oleksandr Palagin
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Directed Evolution Methods for Enzyme Engineering
Molecules, 2021 Enzymes underpin the processes required for most biotransformations. However, natural enzymes are often not optimal for biotechnological uses and must be engineered for improved activity, specificity and stability.
Saurabh Rajendra Nirantar
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RNA-mediated in vivo Directed Evolution in Yeast
Bio-Protocol, 2022 Directed evolution is a powerful approach to obtain genetically-encoded sought-for traits. Compared to the prolonged adaptation regimes to mutations occurring under natural selection, directed evolution unlocks rapid screening and selection of mutants ...
Emil Jensen, Michael Jensen
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Models for the directed evolution of bacterial allelopathy: bacteriophage lysins [PDF]
PeerJ, 2015 Microbes produce a variety of compounds that are used to kill or suppress other species. Traditional antibiotics have their origins in these natural products, as do many types of compounds being pursued today in the quest for new antibacterial drugs ...
James J. Bull +3 more
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Recent Advances in Directed Yeast Genome Evolution
Journal of Fungi, 2022 Saccharomyces cerevisiae, as a Generally Recognized as Safe (GRAS) fungus, has become one of the most widely used chassis cells for industrial applications and basic research.
Zhen Yao, Qinhong Wang, Zongjie Dai
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Directed evolution: selection of the host organism
Computational and Structural Biotechnology Journal, 2012 Directed evolution has become a well-established tool for improving proteins and biological systems. A critical aspect of directed evolution is the selection of a suitable host organism for achieving functional expression of the target gene.
Azadeh Pourmir, Tyler W Johannes
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Directed Evolution of a Mycobacteriophage
Antibiotics, 2019 Bacteriophages represent an alternative strategy to combat pathogenic bacteria. Currently, Mycobacterium tuberculosis infections constitute a major public health problem due to extensive antibiotic resistance in some strains.
María Cebriá-Mendoza +2 more
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Towards the Directed Evolution of Artificial Metalloenzymes
CHIMIA, 2021 Artificial metalloenzymes (ArMs) are a class of enzymes holding great promise. In contrast to natural enzymes, the core of ArMs is a synthetic metallocofactor, with potential for bio-orthogonal reactivity, incorporated within a host protein.
Jaicy Vallapurackel
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Evolution of a Student Directed Free Clinic
Journal of Regional Medical Campuses, 2023 This report summarizes the 20 year evolution of community engagement at a small regional rural campus. The process includes establishing a student directed free clinic and its transition through the wider availability of Medicaid expansion.
William J. Crump +3 more
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