Results 41 to 50 of about 11,830,288 (332)
Computationally Optimizing the Directed Evolution of Proteins [PDF]
, 2003 Directed evolution has proven a successful strategy for protein engineering. To accelerate the discovery process, we have developed several computational methods to optimize the mutant libraries by targeting specific residues for mutagenesis, and ...
Voigt, Christopher Ashby
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Parent-Offspring Conflict and the Evolution of Infant-Directed Song
, 2022 We present a theory of the origin and evolution of infant-directed song, a form of music found in many cultures. After examining the ancestral ecology of parent-infant relations, we propose that infant-directed song arose in an evolutionary arms race ...
Mehr, Samuel, Krasnow, Max
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Reintroducing the direction of evolution
Religion, Brain & Behavior, 2023 Vidal, C. 2023. “Reintroducing the Direction of Evolution.” Religion, Brain & Behavior 13 (4). Routledge: 474–77. doi:10.1080/2153599X.2022.2143405. https://doi.org/10.1080/2153599X.2022.2143405.
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Directing evolution in cells [PDF]
Nature Methods, 2020 A CRISPR–Cas9-based approach generates libraries of mutant proteins targeted to specific subcellular compartments for in situ directed evolution.
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Self-directed multimodal learning in higher education [PDF]
, 2020 This book aims to provide an overview of theoretical and practical considerations in terms of self-directed multimodal learning within the university context.
Bailey, Roxanne +9 more
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Recent Advances in Directed Yeast Genome Evolution
Journal of Fungi, 2022 Saccharomyces cerevisiae, as a Generally Recognized as Safe (GRAS) fungus, has become one of the most widely used chassis cells for industrial applications and basic research.
Zhen Yao, Qinhong Wang, Zongjie Dai
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Cluster learning-assisted directed evolution
Nature Computational Science, 2021 Directed evolution, a strategy for protein engineering, optimizes protein properties (that is, fitness) by expensive and time-consuming screening or selection of a large mutational sequence space.
Yu-Chi Qiu, Jian Hu, Guo-Wei Wei
semanticscholar +1 more source
Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]
, 2012 Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
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Using continuous directed evolution to improve enzymes for plant applications
bioRxiv, 2021 Continuous directed evolution of enzymes and other proteins in microbial hosts is capable of outperforming classical directed evolution by executing hypermutation and selection concurrently in vivo, at scale, with minimal manual input.
J. García-García +7 more
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Towards the Directed Evolution of Artificial Metalloenzymes
CHIMIA, 2021 Artificial metalloenzymes (ArMs) are a class of enzymes holding great promise. In contrast to natural enzymes, the core of ArMs is a synthetic metallocofactor, with potential for bio-orthogonal reactivity, incorporated within a host protein.
Jaicy Vallapurackel
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