Results 51 to 60 of about 11,830,288 (332)
Directed polymerase evolution [PDF]
FEBS Letters, 2013 Polymerases evolved in nature to synthesize DNA and RNA, and they underlie the storage and flow of genetic information in all cells. The availability of these enzymes for use at the bench has driven a revolution in biotechnology and medicinal research; however, polymerases did not evolve to function efficiently under the conditions required for some ...
Chen, Tingjian, Romesberg, Floyd E.
openaire +2 more sources
Directed Evolution of a Ketone Synthase for Efficient and Highly Selective Functionalization of Internal Alkenes by Accessing Reactive Carbocation Intermediates [PDF]
, 2022 Gergel S, Soler J, Klein A, et al. Directed Evolution of a Ketone Synthase for Efficient and Highly Selective Functionalization of Internal Alkenes by Accessing Reactive Carbocation Intermediates. ChemRxiv.
Hauer, Bernhard +20 more
core +2 more sources
Evolution of a Student Directed Free Clinic
Journal of Regional Medical Campuses, 2023 This report summarizes the 20 year evolution of community engagement at a small regional rural campus. The process includes establishing a student directed free clinic and its transition through the wider availability of Medicaid expansion.
William J. Crump +3 more
doaj +1 more source
Directed Evolution of Aptamer Discovery Technologies
bioRxiv, 2021 Conspectus Although antibodies are a powerful tool for molecular biology and clinical diagnostics, there are many emerging applications for which nucleic acid-based aptamers can be advantageous.
Diana Wu +4 more
semanticscholar +1 more source
THE DIRECTION OF HUMAN EVOLUTION [PDF]
The Journal OF Nervous and Mental Disease, 1922 n ...
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Directed evolution of improved zinc finger methyltransferases. [PDF]
PLoS ONE, 2014 The ability to target DNA methylation toward a single, user-designated CpG site in vivo may have wide applicability for basic biological and biomedical research.
Brian Chaikind, Marc Ostermeier
doaj +1 more source
Cis Elements: Added Boost to the Directed Evolution of Plant Genes
Journal of Pure and Applied Microbiology, 2022 To increase the expression of a native/foreign plant/bacterial gene, the complete network of cis-elements must be excavated to increase its biosynthetic yield, especially under industrial stress conditions.
Harisomayajula Valli +6 more
doaj +1 more source
Disaccharide phosphorylases: Structure, catalytic mechanisms and directed evolution
Synthetic and Systems Biotechnology, 2021 Disaccharide phosphorylases (DSPs) are carbohydrate-active enzymes with outstanding potential for the biocatalytic conversion of common table sugar into products with attractive properties. They are modular enzymes that form active homo-oligomers. From a
Shangshang Sun, Chun You
doaj +1 more source
Systematic Directed Evolution. (PRANCE).
, 2021 Real-time monitoring data for PRANCE directed evolution. Raw data contained in .db files and annotated with associated manifest.csv files. NGS files for qtRNA population sequencing are uploaded as FASTQ files, with associated barcode files for each qtRNA
Chory, E (via Mendeley Data) +1 more
core +1 more source
Directed Evolution of Enzymes:Library Screening Strategies [PDF]
, 2009 Directed evolution has become the preferred engineering approach to generate tailor-made enzymes. The method follows the design guidelines of nature: Darwinian selection of genetic variants.
Dijkhuizen, Lubbert; id_orcid +3 more
core +1 more source