Results 21 to 30 of about 286,859 (297)

Directed Evolution of an Efficient and Thermostable PET Depolymerase

, 2021
The recent discovery of a hydrolytic enzyme, IsPETase, that can deconstruct poly(ethylene) terephthalate (PET), has sparked great interest in biocatalytic approaches to recycle plastics.
Philip, Day, Michael, Shaver, Florence, Hardy, Arthur, Garforth, Colin, Levy, Aleksander, Tedstone, Saranarayanan, Ramachandran, Jake, Foster, Anthony, Green, Elizabeth , Bell, Sarah , Haigh, Siobhan, Kilbride, Ross, Smithson   +12 more
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Evolution of a Student Directed Free Clinic

Journal of Regional Medical Campuses, 2023
This report summarizes the 20 year evolution of community engagement at a small regional rural campus. The process includes establishing a student directed free clinic and its transition through the wider availability of Medicaid expansion.
William J. Crump, Alyssa Hounshell, Micah Kaiser, Kathleen Wilmes   +3 more
doaj   +1 more source

Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]

, 2012
Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
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Recent Advances in Directed Yeast Genome Evolution

Journal of Fungi, 2022
Saccharomyces cerevisiae, as a Generally Recognized as Safe (GRAS) fungus, has become one of the most widely used chassis cells for industrial applications and basic research.
Zhen Yao, Qinhong Wang, Zongjie Dai
doaj   +1 more source

NMR-guided directed evolution

Nature, 2021
Abstract Directed evolution can rapidly achieve dramatic improvements in the properties of a protein or bestow entirely new functions on it. We have discovered a strong correlation between the probability of finding a productive mutation at a particular position of a protein and a chemical shift perturbation in Nuclear Magnetic Resonance ...
Sagar Bhattacharya, Eleonora G. Margheritis, Katsuya Takahashi, Alona Kulesha, Areetha D’Souza, Inhye Kim, Jennifer H. Yoon, Jeremy R. H. Tame, Alexander N. Volkov, Olga V. Makhlynets, Ivan V. Korendovych   +10 more
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A directed mutation operator for real coded genetic algorithms [PDF]

, 2010
Copyright @ Springer-Verlag Berlin Heidelberg 2010.Developing directed mutation methods has been an interesting research topic to improve the performance of genetic algorithms (GAs) for function optimization. This paper introduces a directed mutation (DM)
Yang, S, Li, Changhe, Shengxiang Yang, Kojero, Imtiaz, Imtiaz Korejo, Yang, Shengxiang, Changhe Li, Li, C, Korejo, I   +8 more
core   +1 more source

Directed evolution of improved zinc finger methyltransferases. [PDF]

PLoS ONE, 2014
The ability to target DNA methylation toward a single, user-designated CpG site in vivo may have wide applicability for basic biological and biomedical research.
Brian Chaikind, Marc Ostermeier
doaj   +1 more source

EnzyHTP Computational Directed Evolution with Adaptive Resource Allocation

, 2023
Directed evolution facilitates enzyme engineering via iterative rounds of mutagenesis. Despite the wide applications of high-throughput screening, building “smart libraries” to effectively identify beneficial variants remains a major challenge in the ...
Zhongyue, Yang, Qianzhen, Shao, Yaoyukun, Jiang   +2 more
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THE DIRECTION OF HUMAN EVOLUTION [PDF]

The Journal OF Nervous and Mental Disease, 1922
n ...
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Reintroducing the direction of evolution

Religion, Brain & Behavior, 2023
Vidal, C. 2023. “Reintroducing the Direction of Evolution.” Religion, Brain & Behavior 13 (4). Routledge: 474–77. doi:10.1080/2153599X.2022.2143405. https://doi.org/10.1080/2153599X.2022.2143405.
openaire   +2 more sources