Results 61 to 70 of about 19,243,848 (252)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Rational-function approximation for fluids interacting via piece-wise constant potentials
Condensed Matter Physics, 2012 The structural properties of fluids whose molecules interact via potentials with a hard-core plus n piece-wise constant sections of different widths and heights are derived using a (semi-analytical) rational-function approximation method. The results are
A. Santos, S.B. Yuste, M. López de Haro
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Rational exchange protocol model based on mixed strategy
网络与信息安全学报, 2016 In the exchange of micropayment protocol, the cost of ensuring fairness by TTP is higher than the value of protocol, in this case the rational exchange protocol is a appropriate choice.
Hong DING,Chang-gen PENG,Qing-qing KUANG
doaj +3 more sources
Time-Domain Fractional Behaviour Modelling with Rational Non-Singular Kernels
AxiomsThis paper proposes a solution to model fractional behaviours with a convolution model involving non-singular kernels and without using fractional calculus. The non-singular kernels considered are rational functions of time. The interest of this class of
Jocelyn Sabatier, Christophe Farges
doaj +1 more source
Remote Sensing, 2018 Earth observation satellites with various spatial, spectral and temporal resolutions provide an invaluable means for mapping and monitoring the Earth’s environments.
Zhenling Ma +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Understanding Markov-Switching Rational Expectations Models [PDF]
We develop a set of necessary and sufficient conditions for equilibria to be determinate in a class of forward-looking Markov-switching rational expectations models and we develop an algorithm to check these conditions in practice. We use three examples,
Roger E.A. Farmer +2 more
core
A rational model of function learning [PDF]
, 2015 Theories of how people learn relationships between continuous variables have tended to focus on two possibilities: one, that people are estimating explicit functions, or two that they are performing associative learning supported by similarity.
Thomas L. Griffiths +7 more
core +1 more source
Shape preserving piecewise rational interpolation [PDF]
, 1983 An explicit representation of a C1 piecewise rational cubic function is developed which can be used to solve the problem of shape preserving interpolation.
Gregory, JA, Delbourgo, R
core +4 more sources