Results 121 to 130 of about 226,626 (309)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Coincidence point and fixed point theorems for rational contractions

open access: yes, 2015
The purpose of this work is to present some coincidence point theorems for singlevalued and multivalued rational contractions. A comparative study of different rational contraction conditions is also presented.
OPREA, Anca Maria
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Some Fixed Point Result in Metric Spaces for Rational Expression

open access: yes, 2014
In the present paper we establish some fixed point theorems in complete metric space taking rational expression. Our Result Generalize the result of many authors.
Tiwari, Ankur   +2 more
core  

Rational number approximation in higher radix floating point systems

open access: yes, 1993
Recent proposals have suggested that suitably encoded non-binary floating point representations might offer range and precision comparable to binary systems of equal word size.
Petry, Frederick E., Johnstone, Paul
core   +1 more source

A conjecture on rational approximations to rational points

open access: yesJournal of Algebraic Geometry, 2006
In this paper, we examine how well a rational point P P on an algebraic variety
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Common Fixed Point Theorems under Rational Inequality

open access: yes, 2013
In this paper we establish common fixed point theorems for two pairs of self maps in a complete metric space by using occasionally weakly biased maps satisfying the property (E.A.) using contraction  condition involving rational expressions.
RAO, G V V JAGANNADHA   +1 more
core  

Rational points on X_0^+ (p^r)

open access: yes, 2011
We show how the recent isogeny bounds due to É. Gaudron and G. Rémond allow to obtain the triviality of X_0^+ (p^r)(Q), for r>1 and p a prime exceeding 2.10^{11}. This includes the case of the curves X_split (p). We then prove, with the help of computer calculations, that the same holds true for p in the range 10 < p < 10^{14}, p\neq 13.
Bilu, Yuri   +2 more
openaire   +4 more sources

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