Results 81 to 90 of about 11,489,693 (332)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Rational points on a subanalytic surface [PDF]

Annales de l'Institut Fourier, 2005
Let X ⊂ ℝ n be a compact subanalytic surface.
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Fixed-Point Theorems for Max-Type Rational Contractions in Quasi-b-Metric Spaces

Journal of Mathematics
In this study, we introduce a new class of contractive mappings, termed max-type rational contractions, and analyze their behavior in comparison with the standard contractions widely used in fixed-point theory. Through illustrative examples, we highlight
Savita Rathee, Nisha Balhara, Anil Kumar, null Minakshi, Anshuka Kadyan   +4 more
doaj   +1 more source

On the limits of non-uniform rational B-spline surfaces with varying weights

Advances in Mechanical Engineering, 2017
The non-uniform rational B-spline is a mathematical model commonly used in computer-aided design and manufacturing. For a non-uniform rational B-spline surface, when a single weight approaches infinity, the surface tends to the corresponding control ...
Yue Zhang, Chun-Gang Zhu, Qing-Jie Guo
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Necessary and Sufficient Conditions for Expressing Quadratic Rational Bézier Curves

Frontiers in Physics, 2020
Quadratic rational Bézier curve transformation is widely used in the field of computational geometry. In this paper, we offer several important characteristics of the quadratic rational Bézier curve.
Chaoyu Yang, Jie Yang, Ying Liu, Xianya Geng   +3 more
doaj   +1 more source

Advances on the fixed point results via simulation function involving rational terms

Advances in Difference Equations, 2021
In this paper, we propose two new contractions via simulation function that involves rational expression in the setting of partial b-metric space. The obtained results not only extend, but also generalize and unify the existing results in two senses: in ...
Erdal Karapınar, Chi-Ming Chen, Maryam A. Alghamdi, Andreea Fulga   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fixed Point Theory in α-Complete Metric Spaces with Applications

Abstract and Applied Analysis, 2014
The aim of this paper is to introduce new concepts of α-η-complete metric space and α-η-continuous function and establish fixed point results for modified α-η-ψ-rational contraction mappings in α-η-complete metric spaces.
N. Hussain, M. A. Kutbi, P. Salimi
doaj   +1 more source