Results 161 to 170 of about 3,799,599 (344)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A rational optimal block hybrid method for enhanced accuracy in solving Lane–Emden equations

Partial Differential Equations in Applied Mathematics
This paper introduces a block hybrid method designed for the effective resolution of Lane–Emden equations, which are characterized as second-order boundary value problems incorporating a singularity at the origin.
Sandile Motsa, Salma Ahmedai, Mpho Nefale, Olumuyiwa Otegbeye   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A few examples of points of finite order on some smooth plane cubics

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2017
In this expository article we give a self-contained presentation on the rational points of finite order on smooth cubics. We mainly construct examples of points of order between four and twelve, except the eleven case of course.
Gioia Failla, Juan Bosco Frias Medina, Mustapha Lahyane   +2 more
doaj   +1 more source

Rational points on X_0^+ (p^r)

, 2011
We show how the recent isogeny bounds due to É. Gaudron and G. Rémond allow to obtain the triviality of X_0^+ (p^r)(Q), for r>1 and p a prime exceeding 2.10^{11}. This includes the case of the curves X_split (p). We then prove, with the help of computer calculations, that the same holds true for p in the range 10 < p < 10^{14}, p\neq 13.
Bilu, Yuri, Parent, Pierre, Rebolledo, Marusia   +2 more
openaire   +4 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The number of rational points of some classes of algebraic varieties over finite fields

Open Mathematics
Let Fq{{\mathbb{F}}}_{q} be the finite field of characteristic pp and Fq*=Fq\{0}{{\mathbb{F}}}_{q}^{* }\left={{\mathbb{F}}}_{q}\backslash \left\{0\right\}.
Zhu Guangyan, Fang Yingjue, Luo Yuanyuan, Lin Zongbing   +3 more
doaj   +1 more source

Tori and surfaces violating a local-to-global principle for rationality

Comptes Rendus. Mathématique
We show that even within a class of varieties where the Brauer–Manin obstruction is the only obstruction to the local-to-global principle for the existence of rational points (Hasse principle), this obstruction, even in a stronger, base change invariant ...
Kunyavskiĭ, Boris
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source