Results 141 to 150 of about 3,799,599 (344)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Abundance of rational points [PDF]
, 2021 For a smooth algebraic variety X defined over a number field K, one could ask several questions about the abundance of its rational points. This thesis revolves, in particular, around the following three properties: Hilbert Property, weak ...
DEMEIO, JULIAN LAWRENCE
core
Nauka ta progres transportu, 2019 Purpose. Taking into account research and improvement of transport and storage processes for loading railway cars with bridge cranes the purpose of the study is the analysis of actual crane operation zones, development of simulation models of their ...
S. M. Turpak +3 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 The purpose of this paper is to study common fixed points in complex valued metric spaces and obtain sufficient conditions for the existence of common fixed points of a pair of mappings satisfying generalized contraction involving rational expressions.
Nashine Hemant Kumar, Fisher Brian
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
The behavior of rational points in families
, 2019 A topic of current interest regards 'how often' a variety has a rational point. This topic was initially studied by Serre who gave upper bounds in the case of families of conics parametrised by a projective space.
Sofos, Efthymios
core
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Optimal spectroscopic measurement design: Bayesian framework for rational data acquisition
Machine Learning: Science and TechnologyWe propose an optimal experimental design method for spectroscopic measurements that can determine the appropriate number and placement of measurement points in a rational manner.
Yusei Ito +3 more
doaj +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source