Results 71 to 80 of about 729,207 (352)
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
The Function of Normative Process‐Requirements [PDF]
, 2012 This paper discusses whether rationality, morality or prudence impose process‐requirements upon us. It has been argued that process‐requirements fulfil two essential functions within a system of rational, moral or prudential requirements. These functions
Fink, Julian
core +1 more source
Judgment and Decision Making, 2018 In many sports contests, the equilibrium requires players to randomize across repeated rounds, i.e., exhibit no temporal predictability. Such sports data present a window into the (in)efficiency of random sequence generation in a natural competitive ...
Leonidas Spiliopoulos
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Adaptive mechanisms of social and asocial learning in immersive collective foraging
Nature CommunicationsHuman cognition is distinguished by our ability to adapt to different environments and circumstances. Yet the mechanisms driving adaptive behavior have predominantly been studied in separate asocial and social contexts, with an integrated framework ...
Charley M. Wu +5 more
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Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
On rational series and rational languages
Theoretical Computer Science, 1998 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Social Influence in Adolescent Decision-Making: A Formal Framework
Frontiers in Psychology, 2019 Adolescence is a period of life during which peers play a pivotal role in decision-making. The narrative of social influence during adolescence often revolves around risky and maladaptive decisions, like driving under the influence, and using illegal ...
Simon Ciranka +4 more
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Rational relations and rational series
Theoretical Computer Science, 1992 The paper deals with noncommutative rational series over an alphabet \(A\) with multiplicities in subsemirings of Rat \(B^*\). It is especially devoted to Fatou extension problems and usual decidability questions (equivalence, intersection, finiteness) concerning such series.
openaire +2 more sources