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Results 1 to 10 of about 12,065 (114)

Five‐Minute Apgar Scores and Its Prognostic Value for Mortality and Severe Morbidity in Very Preterm Infants: A Multinational Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine associations between a 5‐min Apgar score < 7 and severe neonatal outcomes in very preterm (VPT) infants and how results are impacted by variations in assigning Apgar scores within an international context. Design Prospective observational population‐based cohort study.
Harald Ehrhardt +79 more
wiley +1 more source

Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging

Aging Cell, EarlyView.
A comprehensive multi‐omic profiling of murine muscle stem cells across three ages and both sexes reveals extensive enhancer and 3D genome rewiring, concomitant with increased inflammation, lineage drift, loss of quiescence, and reduced myogenic potential.
Changyou Shi +17 more
wiley +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic +9 more
wiley +1 more source

Real‐World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors

Acta Paediatrica, Volume 114, Issue 11, Page 2874-2884, November 2025.
ABSTRACT Aim This study assessed neurodevelopmental outcomes in neonates with hypoxic‐ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH) outside randomised controlled trials (RCTs). It also aimed to identify predictors of outcomes and evaluate TH practices across centres.
Luca Bedetti +23 more
wiley +1 more source

Comparative Genomic Analysis of Co‐Occurring Hybrid Zones of House Mouse Parasites Pneumocystis murina and Syphacia obvelata Using Genome Polarisation

Molecular Ecology, Volume 34, Issue 21, November 2025.
ABSTRACT Parasites are expected to hybridise in similar ways to free‐living organisms, although this may be modified by their reduced genome architecture. Recombinant strains and taxa of hybrid origin can be studied in nature where hosts come into secondary contact. Here we apply genome‐wide analysis to parasites from a contact previously characterised
Jan Petružela +9 more
wiley +1 more source

Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats

Aging Cell, Volume 24, Issue 8, August 2025.
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura +15 more
wiley +1 more source

Less Invasive Surfactant Administration Versus Intubate‐Surfactant‐Extubate: Associated With Reduced Mechanical Ventilation in Extremely Preterm Infants

Acta Paediatrica, Volume 114, Issue 8, Page 1868-1876, August 2025.
ABSTRACT Aim To compare less invasive surfactant administration (LISA) and intubation‐surfactant‐extubation (INSURE) in infants born before 28 weeks gestational age (GA) by the need for mechanical ventilation (MV). Methods LISA was introduced in 2017 in our unit without formal prior LISA‐specific training as an equal alternative to INSURE.
C. Heiring +9 more
wiley +1 more source

Genetic Consequences of Tree Planting Versus Natural Colonisation: Implications for Afforestation Programmes in the United Kingdom

Evolutionary Applications, Volume 18, Issue 8, August 2025.
ABSTRACT The United Kingdom aims to dramatically accelerate the establishment of new woodlands by 2050, yet the impact of different afforestation strategies on landscape genetic diversity and resilience remains unclear. This study integrates environmental data, whole‐genome sequencing and phenotypic assessments to compare bioclimatic envelopes, genetic
Guillermo Friis +8 more
wiley +1 more source

The practice and promise of temporal genomics for measuring evolutionary responses to global change

Molecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract Understanding the evolutionary consequences of anthropogenic change is imperative for estimating long‐term species resilience. While contemporary genomic data can provide us with important insights into recent demographic histories, investigating past change using present genomic data alone has limitations.
René D. Clark +9 more
wiley +1 more source

Performance of cryptogenic new onset refractory status epilepticus score in a Brazilian cohort after testing for antineuronal antibodies with tissue‐based and cell‐based assays

Epilepsia, Volume 66, Issue 7, Page 2285-2294, July 2025.
Abstract Objective This study was undertaken to describe a case series of Brazilian new onset refractory status epilepticus (NORSE) patients and evaluate the sensitivity and specificity of a clinical score to predict cryptogenic etiology (c‐NORSE score) after autoimmune encephalitis (AE) testing.
João Henrique Fregadolli Ferreira +42 more
wiley +1 more source

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