Induction of lymphokine-activated killer activity in rat splenocyte cultures: The importance of 2-mercaptoethanol and indomethacin [PDF]
The role of 2-mercaptoethanol and indomethacin in the induction of lymphokine-activated killer (LAK) activity by interleukin-2 (IL-2) in rat splenocyte cultures was investigated.
A Nii +38 more
core +1 more source
Applying refinement to the use of mice and rats in rheumatoid arthritis research [PDF]
Rheumatoid arthritis (RA) is a painful, chronic disorder and there is currently an unmet need for effective therapies that will benefit a wide range of patients. The research and development process for therapies and treatments currently involves in vivo
A Dinda +86 more
core +2 more sources
Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]
Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core +1 more source
Development of the metabolic syndrome is detennined by a complex interaction of environmental and genetic factors and as with other complex human traits, disease gene identification is problematic due to a lack of statistical power and genetic ...
Maciver, Fiona, Maciver, Fiona
core
Identification of donor hematopoietic progenitor cells after allogeneic liver transplantation [PDF]
Demetris, AJ +4 more
core +1 more source
Positive, warm T cell crossmatch in cardiac transplantation: With transient vasculitis and without hyperacute rejection [PDF]
Bahnson, HT +6 more
core +1 more source
Positional identification of variants of Adamts16 linked to inherited hypertension [PDF]
A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.
Achinike, Ovokeraye H. +25 more
core
Genome-Wide Fine-Mapping Of Diabetic Traits [PDF]
Type 2 diabetes results from both genes and the environment. Mapping genetic loci in animal models can help identify genes that are involved in type 2 diabetes to better understand the disease.
Baur, Brittany
core +1 more source
Immunological Rejection in a Heterotopic Rat Liver Transplant Model. [PDF]
Thompson C +10 more
europepmc +1 more source

