Results 51 to 60 of about 5,907 (142)

Tests of evolutionary and genetic rescue using flour beetles, Tribolium castaneum, experimentally evolved to thermal conditions

Ecology and Evolution, Volume 14, Issue 5, May 2024.
We use experimental evolution to test the effects of demographic and evolutionary rescue in populations of Tribolium castaneum previously adapted to high temperature and kept at small population sizes. We find no evidence of rescue in these populations and discuss the results in the context of conservation intervention.
Rebecca Lewis, Michael D. Pointer, Lucy Friend, Matthew J. G. Gage, Lewis G. Spurgin   +4 more
wiley   +1 more source

The origin, connectivity, and individual specialization of island wolves after deer extirpation

Ecology and Evolution, Volume 14, Issue 4, April 2024.
We applied DNA metabarcoding and SNP genotyping to quantify variation in marine foraging behavior within wolf packs, among sexes, and individuals using 957 scats collected from an island and the adjacent mainland from 2016 to 2022. Island wolves consistently consumed sea otters while mainland wolves fed mainly on ungulates and voles with more variation
Charlotte E. Eriksson, Gretchen H. Roffler, Jennifer M. Allen, Alex Lewis, Taal Levi   +4 more
wiley   +1 more source

Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation [PDF]

, 2008
The interaction of donor passenger leukocytes and host leukocytes in recipient secondary lymphoid tissues during the early posttransplantation period is crucial in directing host immune reactions toward allograft rejection or acceptance.
Akdis, Benichou, Buiting, Cebon, Csencsits, Dai, Demetris, Demetris, Demetris, Fleisch, Ganta, Gould, Heeger, Huitinga, Ichikawa, Josien, Jurcevic, Ko, Konieczny, Lakkis, Larsen, Lechler, Mellor, Munn, Murase, Murase, Murase, Nakao, Neto, Nikolic, Okuda, Rabinovich, Raisanen-Sokolowski, Sawitzki, Sekine, Sims, Slegers, Smith, Starzl, Starzl, Sun, Talmage, Van Rooijen, Van Rooijen, Van Rooijen, Wu, Yagihashi, Yan, Zhang   +48 more
core   +2 more sources

Limits to species distributions on tropical mountains shift from high temperature to competition as elevation increases

Ecological Monographs, Volume 94, Issue 1, February 2024.
Abstract Species turnover with elevation is a widespread phenomenon and provides valuable information on why and how ecological communities might reorganize as the climate warms. It is commonly assumed that species interactions are more likely to set warm range limits, while physiological tolerances determine cold range limits.
Jinlin Chen, Owen T. Lewis
wiley   +1 more source

Positional identification of variants of Adamts16 linked to inherited hypertension [PDF]

, 2017
A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.
Achinike, Ovokeraye H., Apte, Suneel S., Bouchard, Claude, Chakravarti, Aravinda, Coe, David, Cooper, Richard S., Ehret, Georg B., Farms, Phyllis, Frank, Bryan C., Ganesh, Santhi K., Garrett, Michael R., Gopalakrishnan, Kathirvel, Joe, Bina, Lee, Norman H., Luu, Truong V., Manickavasagam, Ezhilarasi, O'Connor, Ashley, Pérusse, Louis, Rankinen, Tuomo, Rao, Dabeeru C., Rapp, John P., Rice, Treva, Saad, Yasser, Toland, Edward J., Weder, Alan B., Yerga-Woolwine, Shane   +25 more
core  

Nervous system‐related tropism of SARS‐CoV‐2 and autoimmunity in COVID‐19 infection

European Journal of Immunology, Volume 54, Issue 1, January 2024.
This review summarizes the current knowledge regarding neurotropism and emerging immune responses in SARS‐CoV‐2 infection. There are direct and indirect effects on the nervous system by SARS‐CoV‐2 infection. Presently, vaccination against SARS‐CoV‐2 is the most effective way of preventing SARS‐CoV‐2 infection of the nervous system. Abstract The effects
Robert Weissert
wiley   +1 more source

FK506 suppression of heart and liver allograft rejection: II: The induction of graft acceptance in rats [PDF]

, 1990
Lewis recipients of orthotopic ACI livers had permanent graft acceptance induced with 3 doses of i.m. FK506 in the early postoperative period. They were studied 100 and 300 days posttransplantation.
Cramer, DV, Dong-Goo, K, Fung, J, Murase, N, Starzl, TE, Todo, S   +5 more
core   +1 more source

Experimental Infection of Bundibugyo Virus in Domestic Swine Leads to Viral Shedding with Evidence of Intraspecies Transmission

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The Ebolavirus genus contains several of the deadliest zoonotic viruses known. One of these, Bundibugyo virus (BDBV), has been the causative agent of two outbreaks of human disease that have resulted in 211 known cases with a case fatality rate of 33.6%.
Charles E. Lewis, Mathieu M. Pinette, Steven M. Lakin, Greg Smith, Mathew Fisher, Estella Moffat, Carissa Embury-Hyatt, Brad S. Pickering, Walter Lilenbaum   +8 more
wiley   +1 more source

Upregulation of Transglutaminase andε(γ-Glutamyl)-Lysine in the Fisher-Lewis Rat Model of Chronic Allograft Nephropathy [PDF]

, 2014
Background. Tissue transglutaminase (TG2), a cross-linking enzyme, modulates deposition of extracellular matrix protein in renal fibrosis. This study aimed to examine TG2 and its cross-link product ε(γ-glutamyl)-lysine in the Fisher-Lewis rat renal ...
Butt, Imran, Da Silva, Michelle, Haylor, John, Johnson, Timothy, Raftery, Andrew, Sanchez-Lara, Armando, Shrestha, Badri, Wagner, Bart   +7 more
core   +3 more sources

Applying refinement to the use of mice and rats in rheumatoid arthritis research [PDF]

, 2015
Rheumatoid arthritis (RA) is a painful, chronic disorder and there is currently an unmet need for effective therapies that will benefit a wide range of patients. The research and development process for therapies and treatments currently involves in vivo
A Dinda, A Julià, A Livingston, AL Whittaker, AM Pulichino, B Bolon, BN Gaskill, BN Gaskill, C Kilkenny, C Kilkenny, CA Christianson, CL Karp, CM Sherwin, D Baker, D Pretzel, D Volker, DB Bas, DD Brand, DJ Langford, DS McQueen, E Hutchinson, Elliot Lilley, European Commission, FC Colpaert, FC Colpaert, FC Colpaert, G Kollias, GK Ford, H Smolian, H Yoshitomi, HB Patel, HB Worp van der, HE Krug, J Havey, JL Hurst, JR Earl, K Gouveia, K Ren, Katherine Knight, KM Kokolus, KR Jacobsen, KSP Abelson, L Bevaart, L Carbone, L Moja, LF Mikkelsen, LM Khachigian, M Bara, M Bianchi, M Neidhart, MH Ullman-Culleré, Michael Seed, Michael Wilkinson, MJ Gentle, MJ Molina-Cimadevila, ML Andersen, MW Festing, N Maicas, N Malik, National Research Council, NJ Osborne, P Hawkins, P Honoré, P Loo Van, P McGonigle, Paul Garside, Penny Hawkins, PH Wooley, R McCarthy, Rachel Armstrong, Richard O. Williams, RS Ulrich, S Ribel-Madsen, SA Tischkau, SC Chan, SG Sotocinal, SG Trivedi, SH Richter, T Montero-Melendez, Tania Boden, TL Vincent, V Baumans, V Marashi, V Strand, W Paska, Y Jasemian, Y Peck   +86 more
core   +2 more sources