Results 31 to 40 of about 16,678 (173)
ABSTRACT Phenylketonuria (PKU) is an inborn error of metabolism leading to phenylalanine (Phe) accumulation and consequent neurological, neurocognitive, and psychiatric symptoms. Pegvaliase, a pegylated recombinant phenylalanine ammonia lyase that metabolizes Phe, effectively reduced blood Phe in phase III studies in the United States. This multicenter,
Yoko Nakajima +6 more
wiley +1 more source
Estudo da associação entre duas regiões do genoma do rato, localizadas nos cromossomos 4 e 7, e a emocionalidade em duas linhagens de ratos selecionadas no teste do campo aberto [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em NeurociênciasAs linhagens de ratos Floripa H e Floripa L, selecionadas bidirecionalmente para extremos de locomoção no centro do ...
Hameister, Thaís Muller
core
ABSTRACT Background Major congenital anomalies (CA) affect 2.3% of livebirths and are associated with lower educational attainment. Understanding attainment trajectories throughout primary school would inform parents, schools and organisations and help plan support.
Joachim Tan +11 more
wiley +1 more source
Genetic analysis of circadian and ultradian locomotor activity rhythms in laboratory rats [PDF]
Obvious differences exist in the daily activity patterns of the LEW/Ztm and ACI/Ztm inbred strains of laboratory rats. The inbred strain ACI/Ztm shows a clear 24-h rhythm of locomotor activity.
Wollnik, Franziska +2 more
core +1 more source
ABSTRACT Aim To test the feasibility and acceptability of a newly developed model of neonatal nurse‐controlled analgesia to manage pain in the post‐operative infant. Design The study utilised a single‐centre two‐arm parallel, unblinded randomised controlled external pilot trial design.
Renee Muirhead +5 more
wiley +1 more source
Respostas comportamentais de nocicepção e ansiedade em duas linhagens de ratos, lewis e SHR, contrastantes para a ansiedade: envolvimento da substância P e dos receptores NK1 [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.A ansiedade, ao mesmo tempo em que é influenciada por fatores genéticos, pode modular a reatividade à dor.
Vendruscolo, Leandro Franco
core
Glucocorticoid negative feedback on the HPA axis in five inbred rat strains
The aim of the present work was to study the influence of altering glucocorticoid negative feedback on both basal activity of the hypothalamic-pituitary-adrenal (HPA) axis and its response to acute stress (tail shock) in five inbred rat strains known to
E. Ronald De Kloet +2 more
core +1 more source
O cromossomo 4 influência comportamentos relacionados à memória em um modelo genético de ratos [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.Os ratos das linhagens Lewis (LEW) e Spontaneously hypertensive rats (SHR) diferem em uma série
Corrêa, Fernanda Junkes
core
We show that females of the stick‐insect Megacrania batesii transfer defensive alkaloids to their offspring, providing a novel example of maternal provisioning. We also provide evidence that provisioning is enhanced by parthenogenetic reproduction in this species.
Ana Caroline Oliveira Vasconcelos +2 more
wiley +1 more source
Abstract Background The characteristic feature of immune cytopenias involves the process of extravascular phagocytosis, wherein macrophages in the spleen and/or liver engage in the destruction of blood cells that have been opsonized by auto‐ or alloantibodies.
Melika Loriamini +4 more
wiley +1 more source

