Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone+30 more
core +1 more source
Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats:mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour [PDF]
Modulation of metabotropic glutamate 2 (mGlu2) receptor function has huge potential for treating psychiatric and neurological diseases. Development of drugs acting on mGlu2 receptors depends on the development and use of translatable animal models of ...
Bienkowski, Przemyslaw+16 more
core +1 more source
Effects of Neonatal Handling on Play and Anxiety in F344 and Lewis Rats
Play is an important part of normal childhood development and seen in many mammals, including rats. To better understand the interplay between genotype and postnatal experiences, the effects of neonatal handling on play were assessed in Lewis (LEW) and ...
Siviy, Stephen M.
core +1 more source
Relationship between nocturnal serotonin surge and melatonin onset in rodent pineal gland [PDF]
BACKGROUND: We have recently reported dynamic circadian rhythms of serotonin (5-HT, 5-hydroxytryptamine) output in the pineal gland of rat, which precedes the onset of N-acetylserotonin (NAS) and melatonin secretion at night.
Borjigin, Jimo, Liu, Tiecheng
core +3 more sources
Unique Regulatory Properties of Mesangial Cells Are Genetically Determined in the Rat
Mesangial cells are glomerular cells of stromal origin. During immune complex mediated crescentic glomerulonephritis (Crgn), infiltrating and proliferating pro-inflammatory macrophages lead to crescent formation.
Behmoaras, J+7 more
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Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation [PDF]
The interaction of donor passenger leukocytes and host leukocytes in recipient secondary lymphoid tissues during the early posttransplantation period is crucial in directing host immune reactions toward allograft rejection or acceptance.
Akdis+48 more
core +2 more sources
Divergent risky decision-making and impulsivity behaviors in Lewis rat substrains with low genetic difference. [PDF]
Gabriel DBK+10 more
europepmc +1 more source
Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]
Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M.+2 more
core
Experimental diabetic animal models to study diabetes and diabetic complications. [PDF]
Athmuri DN, Shiekh PA.
europepmc +1 more source
Long survival in rats after multivisceral versus isolated small-bowel allotransplantation under FK 506 [PDF]
Abdominal multivisceral allotransplantation (MVTX) from Brown Norway donor rats to Lewis recipient rats was performed under a 14-day course of low (0.32 mg/kg) or high-dose (0.64 mg/kg) intramuscular FK 506 to which weekly further injections were added ...
Demetris, AJ+6 more
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