Results 61 to 70 of about 16,395 (167)

Applying refinement to the use of mice and rats in rheumatoid arthritis research [PDF]

, 2015
Rheumatoid arthritis (RA) is a painful, chronic disorder and there is currently an unmet need for effective therapies that will benefit a wide range of patients. The research and development process for therapies and treatments currently involves in vivo
A Dinda, A Julià, A Livingston, AL Whittaker, AM Pulichino, B Bolon, BN Gaskill, BN Gaskill, C Kilkenny, C Kilkenny, CA Christianson, CL Karp, CM Sherwin, D Baker, D Pretzel, D Volker, DB Bas, DD Brand, DJ Langford, DS McQueen, E Hutchinson, Elliot Lilley, European Commission, FC Colpaert, FC Colpaert, FC Colpaert, G Kollias, GK Ford, H Smolian, H Yoshitomi, HB Patel, HB Worp van der, HE Krug, J Havey, JL Hurst, JR Earl, K Gouveia, K Ren, Katherine Knight, KM Kokolus, KR Jacobsen, KSP Abelson, L Bevaart, L Carbone, L Moja, LF Mikkelsen, LM Khachigian, M Bara, M Bianchi, M Neidhart, MH Ullman-Culleré, Michael Seed, Michael Wilkinson, MJ Gentle, MJ Molina-Cimadevila, ML Andersen, MW Festing, N Maicas, N Malik, National Research Council, NJ Osborne, P Hawkins, P Honoré, P Loo Van, P McGonigle, Paul Garside, Penny Hawkins, PH Wooley, R McCarthy, Rachel Armstrong, Richard O. Williams, RS Ulrich, S Ribel-Madsen, SA Tischkau, SC Chan, SG Sotocinal, SG Trivedi, SH Richter, T Montero-Melendez, Tania Boden, TL Vincent, V Baumans, V Marashi, V Strand, W Paska, Y Jasemian, Y Peck   +86 more
core   +2 more sources

Unique Regulatory Properties of Mesangial Cells Are Genetically Determined in the Rat

, 2014
Mesangial cells are glomerular cells of stromal origin. During immune complex mediated crescentic glomerulonephritis (Crgn), infiltrating and proliferating pro-inflammatory macrophages lead to crescent formation.
Behmoaras, J, Chiu, L-Y, Cook, HT, Dazzi, F, Lai, P-C, Petretto, E, Srivastava, P, Trento, C   +7 more
core   +3 more sources

Divergent risky decision-making and impulsivity behaviors in Lewis rat substrains with low genetic difference. [PDF]

Behav Neurosci, 2023
Gabriel DBK, Liley AE, Franks HT, Minnes GL, Tutaj M, Dwinell MR, de Jong TV, Williams RW, Mulligan MK, Chen H, Simon NW.   +10 more
europepmc   +1 more source

Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]

, 1997
Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M., Kristal, Dr. M.B., Torres, Dr. G.   +2 more
core  

Identification of donor hematopoietic progenitor cells after allogeneic liver transplantation [PDF]

, 1997
Demetris, AJ, Murase, N, Sakamoto, T, Starzl, TE, Ye, Q   +4 more
core   +1 more source

Leptin signal transduction underlies the differential metabolic response of LEW and WKY rats to cafeteria diet.

Journal of Molecular Endocrinology, 2016
N. Martínez-Micaelo, N. Gonzalez-Abuin, A. Ardévol, M. Pinent, E. Petretto, J. Behmoaras, M. Blay   +6 more
semanticscholar   +1 more source

Influence of daily oral prophylactic selenium treatment on the dibutyltin dichloride (DBTC)-induced pancreatitis in rats [PDF]

Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of propagation of acinar cell injury in acute pancreatitis.
Berg, A., Görl, N., Hennighausen, G., Lemke, M., Merkord, J., Ramer, R., Weber, H.   +6 more
core   +1 more source

Experimental diabetic animal models to study diabetes and diabetic complications. [PDF]

MethodsX, 2023
Athmuri DN, Shiekh PA.
europepmc   +1 more source

Long survival in rats after multivisceral versus isolated small-bowel allotransplantation under FK 506 [PDF]

, 1991
Abdominal multivisceral allotransplantation (MVTX) from Brown Norway donor rats to Lewis recipient rats was performed under a 14-day course of low (0.32 mg/kg) or high-dose (0.64 mg/kg) intramuscular FK 506 to which weekly further injections were added ...
Demetris, AJ, Fung, J, Matsuzaki, T, Murase, N, Starzl, TE, Todo, S, Yagihashi, A   +6 more
core  

A Genetically Heterogeneous Rat Model with Divergent Mitochondrial Genomes. [PDF]

J Gerontol A Biol Sci Med Sci, 2023
Sathiaseelan R, Ahn B, Stout MB, Logan S, Wanagat J, Nguyen HVM, Hord NG, Vandiver AR, Selvarani R, Ranjit R, Yarbrough H, Masingale A, Miller BF, Wolf RF, Austad SN, Richardson A.   +15 more
europepmc   +1 more source