OBJETIVOS: Avaliar a função hepática de ratos hipertensos submetidos a baixa ou alta pressão de pneumoperitônio. MÉTODOS: Foram utilizados 60 ratos, distribuídos em dois grupos (n= 30), de acordo com a pressão de pneumoperitônio de 4 e 10mmHg, sendo 15 ...
Valéria Vieira Chida +6 more
doaj +1 more source
Necessity for research directed at stimulant type and treatment-onset age to access the impact of medication on drug abuse vulnerability in teenagers with ADHD [PDF]
Controversy continues regarding increased vulnerability for addiction to cocaine and other drugs of abuse in adulthood following the use of stimulant medications for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
Dwoskin, Linda P., Kantak, Kathleen M.
core +1 more source
A função renal de ratos espontaneamente hipertensos submetidos ao pneumoperitônio
Objetivo: Estudar a função renal de ratos espontaneamente hipertensos submetidos ao pneumoperitônio com CO2. Métodos: Foram utilizados 60 ratos, sendo 30 Wistar SHR e 30 EPM-1 Wistar, com idade ao redor de quatro meses, com peso médio de 341g.
Márcia Bento Moreira +5 more
doaj +1 more source
Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC +34 more
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Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety
The relationship between anxiety-related behaviors and voluntary ethanol intake was examined in two pairs of rat lines by the oral ethanol self-administration procedure. Floripa high (H) and low (L) rats selectively bred for contrasting anxiety responses
G.E. Da Silva, A. Ramos, R.N. Takahashi
doaj +1 more source
Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3 [PDF]
Background: We have previously confirmed the importance of rat chromosome 3 (RNO3) genetic loci on blood pressure elevation, pulse pressure (PP) variability and renal pathology during salt challenge in the stroke-prone spontaneously hypertensive (SHRSP ...
Beattie, Wendy +8 more
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Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD [PDF]
Impulsivity and hyperactivity are two facets of attention deficit/hyperactivity disorder (ADHD). Impulsivity is expressed as reduced response inhibition capacity, an executive control mechanism that prevents premature execution of an intermittently ...
Bardo, M. T. +3 more
core +1 more source
PURPOSE: Evaluation of colonic healing in spontaneously hypertensive rats. METHODS: Fifty male, young and inbred rats were used. Twenty-five Wistar Kyoto rats (WKY) as control and twenty-five spontaneously hypertensive rats (SHR) as an experimental group.
Gilberto Luiz Ortolan +5 more
doaj +1 more source
Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood [PDF]
Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Dwoskin, Linda P. +3 more
core +1 more source

