Results 91 to 100 of about 68,889 (251)

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

The FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi, Myra Gartner, Claris Simovich, Lihi Gershon, Alexander Brandis, Ehud Gazit, Dana Laor Bar‐Yosef   +6 more
wiley   +1 more source

Using liquid chromatography mass spectrometry (LC-MS) to assess the effect of age, high-fat diet, and rat strain on the liver metabolome.

PLoS ONE, 2020
The goal of this study was to use liquid chromatography mass spectrometry to assess metabolic changes of two different diets in three distinct rat strains.
Greg Boyce, Mohammad Shoeb, Vamsi Kodali, Terence Meighan, Jenny R Roberts, Aaron Erdely, Michael Kashon, James M Antonini   +7 more
doaj   +1 more source

The power of a stewardship mind: Reorienting organizations around the duty to care to better address grand challenges

International Journal of Management Reviews, EarlyView.
Abstract The present article presents an integrative review related to stewardship in all the business and management disciplines, from its initial development in 1980 to the present. Specifically, we applied a latent Dirichlet allocation‐based topic modelling analysis to almost 1200 articles, seeking to creatively synthesize the concept of stewardship
Debora Casoli, Marco Visentin, Annamaria Tuan, Giuseppe Cappiello   +3 more
wiley   +1 more source

Digit ratio (2Dratio4D) differences between 20 strains of inbred mice.

PLoS ONE, 2009
The second to fourth digit ratio (2Dratio4D) is sexually differentiated in a variety of species, including humans, rats, birds, and lizards. In humans, this ratio tends to be lower in males than in females.
Reginia H Y Yan, Mark Bunning, Douglas Wahlsten, Peter L Hurd   +3 more
doaj   +1 more source

Use of Cluster Analysis for Identifying Metafounders

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In the metafounder approach, the relationship matrix of metafounders, Γ$$ \boldsymbol{\Gamma} $$ is used to transfer information on relationships between pedigree founders into the numerator relationship matrix A$$ \mathbf{A} $$, creating matrix AΓ$$ {\mathbf{A}}^{\boldsymbol{\Gamma}} $$.
Christine Anglhuber, Christian Edel, Eduardo C. G. Pimentel, Reiner Emmerling, Kay‐Uwe Götz, Georg Thaller   +5 more
wiley   +1 more source

Mitochondrial DNA phylogeography of the Norway rat.

PLoS ONE, 2014
Central Eastern Asia, foremost the area bordering northern China and Mongolia, has been thought to be the geographic region where Norway rats (Rattus norvegicus) have originated.
Ying Song, Zhenjiang Lan, Michael H Kohn
doaj   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

The HaMYB22–HaGST3.2 module mediates salt stress response in sunflower

Journal of Integrative Plant Biology, EarlyView.
The transcription factors HaMYB22, HaMYB120, and HaMYB121 cooperatively activate the transcription of the glutathione S‐transferase gene HaGST3.2, thereby facilitating the removal of reactive oxygen species induced by salt stress in sunflowers and improving their salt tolerance.
Siqi Zhang, Yuliang Han, Qixiu Huang, Weijun Guo, Shurui Dong, Xinxin Li, Qian Zhang, Juncheng Zhang, Yijun Meng, Zhonghua Lei, Maohong Cai, Tao Chen   +11 more
wiley   +1 more source

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, EarlyView.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source