Results 91 to 100 of about 50,502 (212)
The Genoeconomics of Impulsive Intertemporal Choice: A Critical Review
Abstract Dr. Warren Bickel tirelessly investigated delay discounting (DD), a behavioral economic index of impulsive decision making, as a determinant of numerous health outcomes. Among the factors that contribute to a person's level of DD, a burgeoning body of research has illuminated its genetic foundations and the extent to which it may be a ...
Wei Q. Deng +5 more
wiley +1 more source
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández +5 more
wiley +1 more source
Use of Cluster Analysis for Identifying Metafounders
ABSTRACT In the metafounder approach, the relationship matrix of metafounders, Γ is used to transfer information on relationships between pedigree founders into the numerator relationship matrix A, creating matrix AΓ. Commonly metafounders are defined based on the available information of the animal (e.g., country, sex, breed) similar to unknown parent
Christine Anglhuber +5 more
wiley +1 more source
PanGraphRNA is an easy‐to‐use platform that improves RNA‐seq analysis by using graph pangenomes instead of a single reference genome. It increases read alignment accuracy, detects important genes missed by traditional methods, and works across major crops, helping researchers obtain more reliable transcriptome results for diverse plant research and ...
Yifan Bu +10 more
wiley +1 more source
Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We used a systematic meta‐analysis of public transcriptional profiling datasets to identify genes and functional gene sets that are differentially expressed ...
Eva M. Geoghegan +11 more
wiley +1 more source
Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez +6 more
wiley +1 more source
Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno +7 more
wiley +1 more source
ABSTRACT Background Immunocompromised children with hematologic malignancies or undergoing allogeneic haematopoietic stem cell transplantation (HSCT) are at high risk for invasive fungal diseases (IFDs). Reported incidence varies considerably due to heterogeneous diagnostic criteria, antifungal strategies and environmental conditions.
Stefano Malvestiti +6 more
wiley +1 more source
Independent Heritability of Aversive Learning Influences on Cocaine-Seeking and Punishment Resistance in Rats. [PDF]
Eid M +5 more
europepmc +1 more source
Beyond Drug Reward: Heritable Sensitivity to Cocaine Aversion as a Determinant of Addiction Vulnerability. [PDF]
D'Ottavio G, Shaham Y.
europepmc +1 more source

