Results 91 to 100 of about 51,546 (213)
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
Biological Reviews, Volume 101, Issue 5, Page 2408-2426, October 2026.ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source
Sample size – not a one‐size‐fits‐all solution
The Journal of Physiology, EarlyView.
Kathryn L. Gatford
wiley +1 more source
Preclinical Evaluation of Bacterial Lysates in Murine Disease Models: A Systematic Review
Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.ABSTRACT Background Bacterial lysates are biologically active preparations obtained by thermal, mechanical, or chemical inactivation of whole bacterial cells, preserving their immunomodulatory properties. Methods This systematic review evaluates preclinical studies published between 2010 and 2025 that investigated bacterial lysates in murine disease ...
Diana‐Larisa Ancuța, Cristin Coman
wiley +1 more source
Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 4, Page 624-636, October 2026.Abstract Infectious diseases remain a leading cause of morbidity and mortality among pediatric transplant recipients, despite significant advances in transplantation management. Vaccination is the most effective strategy to prevent infections; however, its efficacy is hindered in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT)
Valeria Casotti +35 more
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin +4 more
wiley +1 more source
European Journal of Haematology, Volume 117, Issue 4, Page 739-749, October 2026.ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo +2 more
wiley +1 more source
Entering the Age of Specificity in T Cell Immunity
Immunological Reviews, Volume 343, Issue 1, October 2026.ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley +1 more source
New Phytologist, Volume 252, Issue 1, Page 260-275, October 2026.Maize regeneration via somatic embryogenesis by ectopic expression of morphogenic factors TaGRF4‐TaGIF1 and ZmBBM. Summary Transformation is an indispensable tool for plant genetics and functional genomics. Although stable transformation in maize is no longer a major obstacle, there remains a need for accessible and efficient methods for academic ...
Zongliang Chen +8 more
wiley +1 more source
ZmDLR9 is required for lateral root development via pre‐rRNA processing in maize
The Plant Journal, Volume 128, Issue 1, October 2026.SUMMARY Pumilio (PUM) proteins comprise an evolutionarily conserved family of sequence‐specific RNA‐binding proteins that act as key post‐transcriptional regulators in eukaryotes. In this study, we identified a maize PUM protein, named ZmDLR9 (Defective in Lateral Root 9), as a positive factor involved in lateral root development.
Daojun Li +9 more
wiley +1 more source