Results 81 to 90 of about 51,546 (213)
To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (
Pamela J. Kaisaki +12 more
doaj +1 more source
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana +2 more
wiley +1 more source
Abstract Rice blast, caused by Magnaporthe oryzae (syn. Pyricularia oryzae), remains a major disease in US rice (Oryza sativa L.) production, highlighting the need for additional resistance loci and continued development of blast‐resistant rice varieties. We evaluated 258 US elite long‐grain breeding lines for resistance to four M.
J. M. Manangkil +9 more
wiley +1 more source
Abstract Aim To explore the experiences of mental health difficulties and access to mental health support among young people with cerebral palsy (CP). Method We used a qualitative descriptive design. Participants were young people with CP aged 13 to 25 years and parents of children with CP (6–25 years).
Manjula Manikandan +15 more
wiley +1 more source
Exploratory quantitative analyses suggested that higher seizure severity and COVID‐era enrollment were associated with lower intervention completion, while qualitative findings identified cumulative caregiver burden, medical instability, competing demands, and perceived intervention fit as contributors to attrition.
Carly Hyde Tillis +10 more
wiley +1 more source
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu +7 more
wiley +1 more source
Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley +1 more source
Proposed model of ZmSPL12‐mediated drought resistance through auxin regulation. Summary Climate change‐induced drought increasingly threatens global maize production. Drought‐adaptive root plasticity in maize depends on auxin signaling, yet how auxin homeostasis is dynamically tuned in response to water deficit remains unclear.
Hua Xu +18 more
wiley +1 more source
Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng +5 more
wiley +1 more source
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma +11 more
wiley +1 more source

