Results 71 to 80 of about 50,502 (212)

New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein

Disease Models & Mechanisms, 2016
The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively.
Ana Isabel Garcia Diaz, Ben Moyon, Philip M. Coan, Neza Alfazema, Lara Venda, Kevin Woollard, Tim Aitman   +6 more
doaj   +1 more source

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

New Phytologist, EarlyView.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source

Sex differences in corneal neovascularization in response to superficial corneal cautery in the rat.

PLoS ONE, 2019
Sex-based differences in susceptibility have been reported for a number of neovascular ocular diseases. We quantified corneal neovascularization, induced by superficial silver nitrate cautery, in male and female inbred albino Sprague-Dawley, inbred ...
Yazad D Irani, Emily Pulford, Lauren Mortimer, Swati Irani, Lisa Butler, Sonja Klebe, Keryn A Williams   +6 more
doaj   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

BEHAVIOR OF RAT NEONATES WITH INHERITED STRESS-INDUCED ARTERIAL HYPERTENSION

Вавиловский журнал генетики и селекции, 2015
The present work concerns the development of locomotor activity, rates of weight gain, vibrissa growth, and time of eyelid opening in two inbred rate strains in the early development.
I. O. Meshkov, T. A. Alekhina, T. A. Moreva   +2 more
doaj  

Chemically Induced Oncogenesis in the Peripheral Nervous System Is Suppressed in Congenic BDIX.BDIV-Mss1 and -Mss7 Rats

G3: Genes, Genomes, Genetics, 2016
Human malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive soft-tissue sarcomas with a poor prognosis that arise either in the context of neurofibromatosis 1 or sporadically.
Bernd Koelsch, Linda van den Berg, Christine Fischer, Bettina Winzen-Reichert, Andrea Kutritz, Andrea Kindler-Röhrborn   +5 more
doaj   +1 more source

Strain-Dependent Differences in Oxygen-Induced Retinopathy in the Inbred Rat

Investigative Opthalmology & Visual Science, 2005
To examine the susceptibilities of different rat strains to oxygen-induced retinopathy, a model of human retinopathy of prematurity.Litters of newborn rats of five inbred strains (Fischer 344 [F344], Dark Agouti [DA], Sprague-Dawley [SD], Wistar-Furth [WF], Lewis [LEW]) and one outbred strain (Hooded Wistar [HW]) were maintained in room air or were ...
van Wijngaarden, Peter, Coster, Douglas John, Brereton, Helen Mary, Gibbins, Ian Lewis, Williams, Keryn Anne   +4 more
openaire   +3 more sources

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

G3: Genes, Genomes, Genetics, 2016
To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (
Pamela J. Kaisaki, Georg W. Otto, Karène Argoud, Stephan C. Collins, Robert H. Wallis, Steven P. Wilder, Anthony C. Y. Yau, Christophe Hue, Sophie Calderari, Marie-Thérèse Bihoreau, Jean-Baptiste Cazier, Richard Mott, Dominique Gauguier   +12 more
doaj   +1 more source