Results 121 to 130 of about 130,261 (276)

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

The Zma‐miRNA319‐ZmMYB74 Module Regulates Maize Resistance to Stalk Rot Disease by Modulating Lignin Deposition

Plant Biotechnology Journal, EarlyView.
ABSTRACT Stalk rot, primarily caused by Fusarium graminearum (Fg) and Pythium inflatum (Pi), is a major maize disease responsible for significant yield losses. The molecular mechanisms governing defence against these pathogens remain poorly understood. To uncover key miRNAs and their regulatory genes, small RNA, degradome, and transcriptome sequencing ...
Yanyong Cao, Juan Ma, Zeqiang Cheng, Laikun Xia, Lifeng Wang, Jingjing Li, Xingrui Zhang, Shengbo Han, Yan‐Ping Tian, Mingjun Li, Zhanyuan Zhang, Jihua Tang, Zaifeng Fan, Tao Zhou, Canxing Duan, Xiang‐Dong Li, Huiyong Li   +16 more
wiley   +1 more source

Molecular targets of alcohol action: translational research for pharmacotherapy development and screening. [PDF]

, 2011
Alcohol abuse and dependence are multifaceted disorders with neurobiological, psychological, and environmental components. Research on other complex neuropsychiatric diseases suggests that genetically influenced intermediate characteristics affect the ...
Addolorato, Alexander-Kaufman, Alte, American Psychiatric Association, Anni, Anton, Anton, Anton, Arkin, Arlinde, Aschner, Atz, Barr, Beck, Beck, Belknap, Bell, Bell, Bell, Bemeur, Bendroth, Bennett, Bennett, Bergeson, Bertsch, Bhardwaj, Bhave, Bierut, Blalock, Blednov, Blizard, Borucki, Bosch-Morell, Brodin, Buck, Bueno, Bull, Butterworth, Butterworth, Caberlotto, Caspi, Chatterjee, Chester, Chi, Ciccocioppo, Cloninger, Colantuoni, Colombo, Colombo, Cotton, Cozzoli, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, Crabbe, D'Souza, Daniels, Davies, Davis, Deken, Demarest, Dev, Dick, Dick, Dick, Dick, Duranceaux, Dutta, Edenberg, Edenberg, Edenberg, Edenberg, Ehlers, Erblich, Eriksson, Eriksson, Etheridge, Evans, Fehr, Fehr, Flatscher-Bader, Foroud, Franke, Freeman, Freeman, Fukuda, Garbutt, Garbutt, Garner, Gelernter, Geschwind, Godefroy, Goldman, Golka, Gorini, Gottesman, Griffiths-Jones, Hariri, Haroutunian, Harper, Harper, Hashimoto, Hassan, Heilig, Heilig, Helander, Higuchi, Hillemacher, Hinckers, Hirano, Hock, Hodge, Hoffman, Hoiseth, Hollander, Hommer, Hood, Hu, Huntley, Husi, Iwamoto, Iwamoto, Jackson, Johnson, Johnson, Johnson, Jones, Kashem, Kashem, Kasinathan, Kaur, Kawahara, Kemming, Kendler, Kerns, Kim, Kimpel, Kissack, Koch, Konkimalla, Koob, Koob, Koob, Kril, Kril, Kurose, Landgraf, Lappalainen, Lavoie, Le, Lea, Lee, Leeman, Leggio, Leggio, Leggio, Leggio, Leggio, Lewohl, Lewohl, Li, Li, Litten, Liu, Liu, Liu, Lock, Loring, Lu, Ludvig, Luthar, Mackay, MacLaren, Maiya, Maiya, Mane, Mann, Marcotte, Mardones, Matsuda-Matsumoto, Matsumoto, Matsumoto, Maycox, Mayfield, Mayfield, Mayfield, McBride, McBride, McBride, McClearn, McClearn, Melo, Merikangas, Merikangas, Miller, Milner, Miranda, Mirin, Mirnics, Mirnics, Mirnics, Mitchell, Mochly-Rosen, Montoliu, Moore, Mor, Morin, Morozova, Mortazavi, Mulligan, Murphy, Murphy, Muth, Nagy, Nestler, Neuhold, Niemela, Noble, Norenberg, Obara, Okutsu, Papagiannakopoulos, Petkov, Pfefferbaum, Phillips, Pietrzykowski, Pongrac, Pragst, Purcell, Quintanilla, Rahman, Ramani, Ratti, Rausch, Reynaud, Rhodes, Richter, Rimondini, Risinger, Roberts, Rodd, Rodd, Rodgers, Rogers, Rounsaville, Saba, Saito, Saito, Sakai, Sathyan, Scheiffele, Schuckit, Schuckit, Schuckit, Schuckit, Schuckit, Schuckit, Shen, Sher, Slutske, Smith, Sokolov, Sommer, Spanagel, Spanagel, Staub, Stephens, Sullivan, Sung, Swift, Swift, Szumlinski, Szumlinski, Tabakoff, Tabakoff, Tabakoff, Tang, Tang, Taracha, Tarantino, Taxman, Thibault, Thiele, Tkachev, Tomita, Treadwell, Vergne, Vetulani, Volavka, Volkow, Wahlsten, Wall, Walter, Wand, Weinshenker, Whitfield, Williams, Winokur, Worst, Wu, Wurst, Wurst, Xu, Yao, Yoneyama, Zembutsu   +309 more
core   +1 more source

Strain-Dependent Differences in Oxygen-Induced Retinopathy in the Inbred Rat

Investigative Opthalmology & Visual Science, 2005
To examine the susceptibilities of different rat strains to oxygen-induced retinopathy, a model of human retinopathy of prematurity.Litters of newborn rats of five inbred strains (Fischer 344 [F344], Dark Agouti [DA], Sprague-Dawley [SD], Wistar-Furth [WF], Lewis [LEW]) and one outbred strain (Hooded Wistar [HW]) were maintained in room air or were ...
van Wijngaarden, Peter, Coster, Douglas John, Brereton, Helen Mary, Gibbins, Ian Lewis, Williams, Keryn Anne   +4 more
openaire   +3 more sources

Developing an Efficient System for Hybrid Rice Seed Production Using Partial Male Sterility

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient production of hybrid rice seeds requires male sterility systems to overcome the challenges of self‐pollination. In this study, we identified male gametic transfer defect (GTrD)5 and GTrD9 as essential genes for the process of male gamete transmission in rice.
Su‐Kyoung Lee, Woo‐Jong Hong, Eui‐Jung Kim, Choonseok Lee, Sunok Moon, Sun‐Hwa Ha, Ki‐Hong Jung   +6 more
wiley   +1 more source

Genetic regulation of mouse liver metabolite levels. [PDF]

, 2014
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and ...
Bennett, Brian J, Che, Nam, Ghazalpour, Anatole, Hagopian, Raffi, He, Aiqing, Kayne, Paul, Kirchgessner, Todd, Lusis, Aldons J, Orozco, Luz, Pan, Calvin, Shih, Diana, Yang, Wen-pin   +11 more
core   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Estrogen-Dependent Upregulation of Adcyap1r1 Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4

Frontiers in Genetics, 2018
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more than ...
John Paul Spence, Jill L. Reiter, Bin Qiu, Hao Gu, Dawn K. Garcia, Lingling Zhang, Tamara Graves, Kent E. Williams, Paula J. Bice, Yi Zou, Zhao Lai, Weidong Yong, Tiebing Liang   +12 more
doaj   +1 more source

Technical considerations and review of urinary microRNAs as biomarkers for chronic kidney disease in dogs and cats

Veterinary Clinical Pathology, EarlyView.
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley   +1 more source

Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Electrocardiographic (ECG) parameters are regarded as intermediate phenotypes of cardiac arrhythmias. Insight into the genetic underpinnings of these parameters is expected to contribute to the understanding of cardiac arrhythmia mechanisms ...
Michiel E. Adriaens, Elisabeth M. Lodder, Aida Moreno‐Moral, Jan Šilhavý, Matthias Heinig, Charlotte Glinge, Charly Belterman, Rianne Wolswinkel, Enrico Petretto, Michal Pravenec, Carol Ann Remme, Connie R. Bezzina   +11 more
doaj   +1 more source