Results 121 to 130 of about 129,705 (270)

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

G3: Genes, Genomes, Genetics, 2016
To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (
Pamela J. Kaisaki, Georg W. Otto, Karène Argoud, Stephan C. Collins, Robert H. Wallis, Steven P. Wilder, Anthony C. Y. Yau, Christophe Hue, Sophie Calderari, Marie-Thérèse Bihoreau, Jean-Baptiste Cazier, Richard Mott, Dominique Gauguier   +12 more
doaj   +1 more source

Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD [PDF]

, 2016
Impulsivity and hyperactivity are two facets of attention deficit/hyperactivity disorder (ADHD). Impulsivity is expressed as reduced response inhibition capacity, an executive control mechanism that prevents premature execution of an intermittently ...
Bardo, M. T., Dwoskin, L. P., Kantak, K. M., Somkuwar, S. S.   +3 more
core   +1 more source

Trans‐QTL Alliance of HKT1 and PHL7 Modulate Salinity Stress Tolerance and Enhance Crop Yield Endurance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Salinity stress can cause significant yield losses in crops because of its major impact on reproductive success. The complexity of salinity stress responses, particularly their tissue‐ and cell‐specific regulation, continues to challenge the translation of molecular insights into tangible crop yield improvements.
Jitendra K. Mohanty, Antima Yadav, Laxmi Narnoliya, Virevol Thakro, Deepanshi Rathore, Shailesh Tripathi, Senjuti Sinharoy, Pinky Agarwal, Swarup K. Parida   +8 more
wiley   +1 more source

Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]

, 2005
In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Borght, Karin van der,, Eggen, Bart J.L.,, Luiten, Paul G.M.,, Wallinga, Alinde E.,, Zee, Eddy A. van der,   +4 more
core   +3 more sources

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

Controlled study of autoimmunization against liver in inbred rat strains [PDF]

Gut, 1971
By prolonged immunization of an inbred rat strain with isologous liver homogenate in Freund's complete adjuvant a low grade autoimmune ;cholangitis' with periductular fibrosis has been demonstrated. The lesion could be transferred to isogeneic animals by serial spleen cell injections and was associated with mild but variable delayed skin sensitivity to
openaire   +3 more sources

The ZmFKF1b‐ZmDi19‐5 Regulatory Module Coordinates Drought Tolerance and Flowering Time in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought is a major environmental stress that inhibits plant growth and reduces crop yields. The Di19 gene family is known to play a pivotal role in mediating plant responses to drought. However, the mechanisms by which Di19 proteins integrate drought response with developmental processes, particularly flowering time, remain largely unknown in ...
Haixia Zeng, Dandan Dou, Yang Yang, Yan Yan, Yawen Sun, Shuhan Yang, Wen Yao, Shifang Zhao, Mingle Wang, Zhixue Liu, Zhenzhen Ren, Huihui Su, Liru Cao, Lixia Ku, Xu Zheng, Chengwei Li, Yanhui Chen   +16 more
wiley   +1 more source

Estrogen-Dependent Upregulation of Adcyap1r1 Expression in Nucleus Accumbens Is Associated With Genetic Predisposition of Sex-Specific QTL for Alcohol Consumption on Rat Chromosome 4

Frontiers in Genetics, 2018
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more than ...
John Paul Spence, Jill L. Reiter, Bin Qiu, Hao Gu, Dawn K. Garcia, Lingling Zhang, Tamara Graves, Kent E. Williams, Paula J. Bice, Yi Zou, Zhao Lai, Weidong Yong, Tiebing Liang   +12 more
doaj   +1 more source

Genome‐Wide Association Study Reveals the Genetic Architecture and Key Drought and Yield Related Genes in Common Vetch (Vicia sativa L.)

Plant Biotechnology Journal, EarlyView.
ABSTRACT Common vetch (Vicia sativa L.) is one of the most economically important annual pasture legumes worldwide. Many factors affect the yield of common vetch; however, the genetic architecture and gene functions associated with common vetch yield have not been explored. On the basis of 115.53 million single‐nucleotide polymorphisms (SNPs) and 18.55
Wenxian Liu, Xianglong Zhao, Yanpeng Li, Qiang Zhou, Iain R. Searle, Wengang Xie, Zhibiao Nan, Zhipeng Liu   +7 more
wiley   +1 more source

Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Electrocardiographic (ECG) parameters are regarded as intermediate phenotypes of cardiac arrhythmias. Insight into the genetic underpinnings of these parameters is expected to contribute to the understanding of cardiac arrhythmia mechanisms ...
Michiel E. Adriaens, Elisabeth M. Lodder, Aida Moreno‐Moral, Jan Šilhavý, Matthias Heinig, Charlotte Glinge, Charly Belterman, Rianne Wolswinkel, Enrico Petretto, Michal Pravenec, Carol Ann Remme, Connie R. Bezzina   +11 more
doaj   +1 more source