Results 11 to 20 of about 50,502 (212)

Quantification of DNA Damage in Different Tissues in Rats with Heart Failure [PDF]

open access: yesArquivos Brasileiros de Cardiologia
Background: Chronic heart failure (CHF) is a complex syndrome which comprises structural and functional alterations in the heart in maintaining the adequate blood demand to all tissues.
Giuseppe Potrick Stefani   +6 more
doaj   +3 more sources

Genetic factors control nicotine self-administration in isogenic adolescent rat strains. [PDF]

open access: yesPLoS ONE, 2012
Adult cigarette smokers usually become dependent on cigarettes during adolescence. Despite recent advances in addiction genetics, little data delineates the genetic factors that account for the vulnerability of humans to smoke tobacco.
Hao Chen   +4 more
doaj   +1 more source

Innate Resistance to Leishmania amazonensis Infection in Rat Is Dependent on NOS2

open access: yesFrontiers in Microbiology, 2021
Leishmania infection causes diverse clinical manifestations in humans. The disease outcome is complicated by the combination of many host and parasite factors.
Yun-Fu Chen   +11 more
doaj   +1 more source

Strain differences in delay discounting using inbred rats [PDF]

open access: yesGenes, Brain and Behavior, 2009
A heightened aversion to delayed rewards is associated with substance abuse and numerous other neuropsychiatric disorders. Many of these disorders are heritable, raising the possibility that delay aversion may also have a significant genetic or heritable component.
C J, Wilhelm, S H, Mitchell
openaire   +2 more sources

Recurrent Regional Allelic Imbalance in Chromosome 15 in Rat Endometrial Adenocarcinomas [PDF]

open access: yesCell Journal, 2010
Objective: Animals of the inbred BDII rat strain are genetically predisposed to endometrialadenocarcinomas (EAC) and can be used to model human cancer.
Ahmad Hamta, Farah Talebbeigy
doaj  

Strain differences in seizure-induced cell death following pilocarpine-induced status epilepticus

open access: yesNeurobiology of Disease, 2012
Mouse strains differ from one another in their susceptibility to seizure-induced excitotoxic cell death. Previously, we have demonstrated that mature inbred strains of mice show remarkable genetic differences in susceptibility to the neuropathological ...
P. Elyse Schauwecker
doaj   +1 more source

Genetic Factors in Animal Models of Intestinal Inflammation

open access: yesCanadian Journal of Gastroenterology, 1995
The critical importance of host genetic susceptibility in determining chronicity, aggressiveness and complications of intestinal inflammation is clearly demonstrated by studies of inbred rodents, transgenic rats and spontaneous mutants. Inbred Lewis rats
R Balfour Sartor
doaj   +1 more source

Worm burdens in outbred and inbred laboratory rats with morphometric data on Syphacia muris (Yamaguti, 1935) Yamaguti, 1941 (Nematoda, Oxyuroidea)

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
Syphacia muris worm burdens were evaluated in the rat Rattus norvegicus of the strains Wistar (outbred), Low/M and AM/2/Torr (inbred), maintained conventionally in institutional animal houses in Brazil. Morphometrics and illustration data for S.
Roberto Magalhães Pinto   +3 more
doaj   +1 more source

Influence of Age and Genetic Background on Ethanol Intake and Behavioral Response Following Ethanol Consumption and During Abstinence in a Model of Alcohol Abuse

open access: yesFrontiers in Behavioral Neuroscience, 2022
Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu   +7 more
doaj   +1 more source

Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety

open access: yesBrazilian Journal of Medical and Biological Research, 2004
The relationship between anxiety-related behaviors and voluntary ethanol intake was examined in two pairs of rat lines by the oral ethanol self-administration procedure. Floripa high (H) and low (L) rats selectively bred for contrasting anxiety responses
G.E. Da Silva, A. Ramos, R.N. Takahashi
doaj   +1 more source

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