Results 41 to 50 of about 23,411 (167)

Morphometric analysis of the phrenic nerve in male and female Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR) [PDF]

open access: yes, 2011
Ventilatory differences between rat strains and genders have been described but the morphology of the phrenic nerve has not been investigated in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats.
FAZAN, V.P.S.   +3 more
core   +3 more sources

Reverse electromechanical modelling of diastolic dysfunction in spontaneous hypertensive rat after sacubitril/valsartan therapy

open access: yesESC Heart Failure, Volume 7, Issue 6, Page 4040-4050, December 2020., 2020
Abstract Aims Hypertension is a significant risk for the development of left ventricular hypertrophy, diastolic dysfunction, followed by heart failure and sudden cardiac death. While therapy with sacubitril/valsartan (SV) reduces the risk of sudden cardiac death in patients with heart failure and systolic dysfunction, the effect on those with diastolic
Yen‐Ling Sung   +6 more
wiley   +1 more source

Strain differences in baroceptor reflex in adult Wistar Kyoto rats

open access: yesClinics, 2010
OBJECTIVES: A subset of normotensive Sprague-Dawley rats show lower baroreflex sensitivity; however, no previous study investigated whether there are differences in baroreflex sensitivity within this subset.
Vitor E. Valenti   +4 more
doaj   +1 more source

Influence of arterial hypertension on colonic healing in rats Influência da hipertensão arterial na cicatrização colônica em ratos

open access: yesActa Cirúrgica Brasileira, 2012
PURPOSE: Evaluation of colonic healing in spontaneously hypertensive rats. METHODS: Fifty male, young and inbred rats were used. Twenty-five Wistar Kyoto rats (WKY) as control and twenty-five spontaneously hypertensive rats (SHR) as an experimental group.
Gilberto Luiz Ortolan   +5 more
doaj   +1 more source

Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains [PDF]

open access: yes, 2009
Background Cognitive function might be affected by the subjects' emotional reactivity. We assessed whether behavior in different tests of emotional reactivity is correlated with performance in aversively motivated learning tasks, using four strains of ...
van der Staay, F.J.   +7 more
core   +2 more sources

Genetic Model to Study the Co-Morbid Phenotypes of Increased Alcohol Intake and Prior Stress-Induced Enhanced Fear Memory

open access: yesFrontiers in Genetics, 2018
Posttraumatic Stress Disorder (PTSD) is a complex illness, frequently co-morbid with depression, caused by both genetics, and the environment. Alcohol Use Disorder (AUD), which also co-occurs with depression, is often co-morbid with PTSD.
Patrick Henry Lim   +6 more
doaj   +1 more source

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

open access: yesDisease Models & Mechanisms, 2017
We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified
Philip M. Coan   +9 more
doaj   +1 more source

Animal models for the study of primary and secondary hypertension in humans. [PDF]

open access: yes, 2016
This is the final version of the article. It first appeared from Spandidos Publications via http://dx.doi.org/10.3892/br.2016.784Hypertension is a significant cause of morbidity and mortality worldwide.
Chan, Yin Wah   +3 more
core   +1 more source

Stress sensitivity and cutaneous sensory thresholds before and after neuropathic injury in various inbred and outbred rat strains.

open access: yesBehavioural Brain Research, 2019
Chronic pain is associated with altered affective state, stress, anxiety and depression. Conversely, stress, anxiety and depression can all modulate pain perception.
Sara Hestehave   +3 more
semanticscholar   +1 more source

Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes [PDF]

open access: yes, 2009
BACKGROUND: Microarray technologies are widely used to quantify the abundance of transcripts corresponding to thousands of genes. To maximise the robustness of transcriptome results, we have tested the performance and reproducibility of rat and mouse ...
Anita Salhan   +6 more
core   +3 more sources

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