Results 1 to 10 of about 448,712 (333)
Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method. [PDF]
PLoS ONE, 2017 Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well ...
Qili He +9 more
doaj +2 more sources
Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]
Respiratory Research, 2016 The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A +17 more
core +2 more sources
Behavioral Phenotyping of Juvenile Long-Evans and Sprague-Dawley Rats: Implications for Preclinical Models of Autism Spectrum Disorders. [PDF]
PLoS ONE, 2016 The laboratory rat is emerging as an attractive preclinical animal model of autism spectrum disorder (ASD), allowing investigators to explore genetic, environmental and pharmacological manipulations in a species exhibiting complex, reciprocal social ...
Bauman, Melissa D +4 more
core +4 more sources
PLoS ONE, 2014 Genetic (G) and environmental (E) manipulations are known to alter behavioural outcomes in rodents, however many animal models of neuropsychiatric disorders only use a restricted selection of strain and housing conditions.
Karly M Turner, Thomas H J Burne
doaj +2 more sources
Biopendix Jurnal Biologi Pendidikan dan Terapan, 2023 Introduction. Sopi is traditional drink from Maluku province which is often consumed in activities related to traditional events. Sopi drink comes from fermented Arenga pinnata which has undergone distillation.
Syahran Wael +3 more
semanticscholar +1 more source
Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
Pharmaceutics, 2022 Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development.
Christine M. Madla +8 more
doaj +1 more source
Oman Medical Journal, 2022 Objectives: We sought to investigate the healing efficacy of thermosensitive in situ gelling formulation containing metronidazole and diclofenac potassium on ligature-induced periodontitis (LIP) in rats. Methods: We used 30 adult male Sprague-Dawley rats;
Nida M. A. Wadi +2 more
doaj +1 more source
Hermaphroditism in a Sprague-Dawley Rat [PDF]
Veterinary Pathology, 2007 A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9–week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the ...
R W, Diters +4 more
openaire +2 more sources
Physiological Reports, 2021 Background Local ischemic preconditioning (IPC) and remote ischemic conditioning (RIC) induced by brief periods of ischemia and reperfusion protect against ischemia‐reperfusion injury.
Thomas Ravn Lassen +6 more
doaj +1 more source
Study on chronic toxicity of rhubarb extract in Sprague-Dawley rats
Heliyon, 2022 Objective: The purpose of this study was to evaluate the safety of rhubarb extract. Methods: SD rats were treated with rhubarb extract at 0, 101, 405 and 1620 mg/kg/day for 52 weeks. food consumption and body weights were recorded.
Wenxiang Yang +7 more
doaj +1 more source