Results 11 to 20 of about 207,124 (265)

Effect of foxtail millet supplementation in comparison to atorvastatin on high-fat diet-induced hyperlipidemia in rats

open access: yesAsian Journal of Medical Sciences, 2023
Background: Hyperlipidemia can be defined as an increased concentration of lipids in the blood. Foxtail millet (FTM) is a nutrient-rich cereal containing several phytochemicals which have possible lipid-lowering and glucose-lowering abilities ...
Praneeth Reddy Onteddu   +4 more
doaj   +1 more source

Urolithiasis in the Sprague-Dawley rat [PDF]

open access: yesLaboratory Animals, 1979
A 7 year collection of calculi from short- and long-term studies with Sprague-Dawley rats showed that although the incidence of rats with urolithiasis was small (0·5%), the variety of sizes and composition of the calculi could be of general interest.
openaire   +2 more sources

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

open access: yesParticle and Fibre Toxicology, 2020
Background Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive.
Astrid Skovmand   +12 more
doaj   +1 more source

Hematoxicity of amodiaquine in sprague-dawley rats

open access: yesToxicology International, 2012
The use of amodiaquine (AQ) and its associated toxic effect has been a major public health concern since cases of life-threatening agranulocytosis and hepatic toxicity were reported during its prophylactic use. The objective of this study was to evaluate the hematological safety profile of AQ therapy.Sprague-Dawley rats were randomly distributed into ...
Saka, W. A.   +3 more
openaire   +3 more sources

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats

open access: yesJournal of Toxicologic Pathology, 2016
Keishibukuryogan is a traditional Japanese medicine widely administered to patients with menopausal symptoms. Because humans use it on a long-term basis, we believed that a carcinogenicity study was warranted. We orally administered keishibukuryogan (TJ-25) extract powder to 6-week-old Sprague-Dawley rats [Crl:CD(SD)], which were divided into four ...
Kanitani, Masanao   +3 more
openaire   +3 more sources

Fatty acid synthase and adipsin mRNA levels in obese and lean JCR:LA-cp rats: effect of diet.

open access: yesJournal of Lipid Research, 1992
In Sprague-Dawley rats, fatty acid synthase (FAS) activity is suppressed by dietary fat. To test the hypothesis that a defect in regulation of de novo fatty acid synthesis exists in massive obesity, we investigated the effect of diet on FAS mRNA levels ...
G Shillabeer   +5 more
doaj   +1 more source

Ovarian Neoplasia in the Sprague-Dawley Rat [PDF]

open access: yesEnvironmental Health Perspectives, 1987
Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor,
openaire   +2 more sources

Systemic candidiasis in Sprague-Dawley rats [PDF]

open access: yesMedical Mycology, 1996
A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
openaire   +2 more sources

Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis

open access: yesActa Veterinaria, 2015
The aim of this study was to investigate the influence of prebiotic inulin diet intervention on the activity of β-glucuronidase and counts of coliforms and lactobacilli in fresh caecal digesta, cytokine levels (IL-6, IL-8) and transcription nuclear ...
Emília Hijová   +5 more
doaj   +1 more source

Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats

open access: yesToxicology Reports, 2020
Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan   +9 more
doaj   +1 more source

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