Results 11 to 20 of about 207,577 (260)

Inhalation of welding fumes reduced sperm counts and high fat diet reduced testosterone levels; differential effects in Sprague Dawley and Brown Norway rats

Particle and Fibre Toxicology, 2020
Background Previous studies have shown that inhalation of welding fumes may induce pulmonary and systemic inflammation and organ accumulation of metal, to which spermatogenesis and endocrine function may be sensitive.
Astrid Skovmand, Aaron Erdely, James M. Antonini, Timothy R. Nurkiewicz, Mohammad Shoeb, Tracy Eye, Vamsi Kodali, Katrin Loeschner, Janja Vidmar, Jørgen S. Agerholm, Sandra Goericke-Pesch, Ulla Vogel, Karin S. Hougaard   +12 more
doaj   +1 more source

Voluntary Alcohol Intake following Blast Exposure in a Rat Model of Mild Traumatic Brain Injury. [PDF]

PLoS ONE, 2015
Alcoholism is a frequent comorbidity following mild traumatic brain injury (mTBI), even in patients without a previous history of alcohol dependence. Despite this correlational relationship, the extent to which the neurological effects of mTBI contribute
Yi Wei Lim, Nathan P Meyer, Alok S Shah, Matthew D Budde, Brian D Stemper, Christopher M Olsen   +5 more
doaj   +1 more source

Acute oral toxicity of zein nanoparticles with encapsulated gamma oryzanol in Sprague Dawley rats [PDF]

E3S Web of Conferences, 2021
Gamma oryzanol (GO) is well known for its antioxidant activity and health-promoting benefits. The gamma oryzanol-loaded zein nanoparticles (GOZNs) were successfully prepared in our previous study. In the present work, the acute oral toxicity of GOZNs was
Rodsuwan Ubonphan, Thisayakorn Krittiya, Thumthanaruk Benjawan, Vatanyoopaisarn Savitri, Uttapap Dudsadee, Zhong Qixin, Rungsardthong Vilai   +6 more
doaj   +1 more source

Effect of foxtail millet supplementation in comparison to atorvastatin on high-fat diet-induced hyperlipidemia in rats

Asian Journal of Medical Sciences, 2023
Background: Hyperlipidemia can be defined as an increased concentration of lipids in the blood. Foxtail millet (FTM) is a nutrient-rich cereal containing several phytochemicals which have possible lipid-lowering and glucose-lowering abilities ...
Praneeth Reddy Onteddu , Suguna Priya , Bhuvaneshwari Gajala , Shravya Edavaluru , Chaitanya Kandula   +4 more
doaj   +1 more source

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats

Journal of Toxicologic Pathology, 2016
Keishibukuryogan is a traditional Japanese medicine widely administered to patients with menopausal symptoms. Because humans use it on a long-term basis, we believed that a carcinogenicity study was warranted. We orally administered keishibukuryogan (TJ-25) extract powder to 6-week-old Sprague-Dawley rats [Crl:CD(SD)], which were divided into four ...
Kanitani, Masanao, Nishimura, Nobuo, Edamoto, Hiroshi, Kase, Yoshio   +3 more
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Ovarian Neoplasia in the Sprague-Dawley Rat [PDF]

Environmental Health Perspectives, 1987
Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor,
openaire   +2 more sources

Systemic candidiasis in Sprague-Dawley rats [PDF]

Medical Mycology, 1996
A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
openaire   +2 more sources

Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis

Acta Veterinaria, 2015
The aim of this study was to investigate the influence of prebiotic inulin diet intervention on the activity of β-glucuronidase and counts of coliforms and lactobacilli in fresh caecal digesta, cytokine levels (IL-6, IL-8) and transcription nuclear ...
Emília Hijová, Alena Śoltésová, Rastislav Salaj, Jozef Kuzma, Ladislav Strojný, Alojz Bomba   +5 more
doaj   +1 more source

Fatty acid synthase and adipsin mRNA levels in obese and lean JCR:LA-cp rats: effect of diet.

Journal of Lipid Research, 1992
In Sprague-Dawley rats, fatty acid synthase (FAS) activity is suppressed by dietary fat. To test the hypothesis that a defect in regulation of de novo fatty acid synthesis exists in massive obesity, we investigated the effect of diet on FAS mRNA levels ...
G Shillabeer, J Hornford, JM Forden, NC Wong, JC Russell, DC Lau   +5 more
doaj   +1 more source

Spontaneous Teratoma in a Sprague-Dawley Rat

Experimental Animals, 1985
An 6-week-old male Sprague-Dawley rat which had undergone no experimental treatment died from enlargement of the abdomen. At necropsy, a spherical mass measuring about 3 X 4cm in diameter was connected to the retroperitoneal region cross to the middorsal line of the body.
T, Itoh, K, Shirota, N, Kagiyama
openaire   +2 more sources