Results 41 to 50 of about 207,124 (265)

Spontaneous Iron Overload in Sprague-Dawley Rats [PDF]

Toxicologic Pathology, 1997
In a review of the toxicological studies performed in our laboratory during the period 1986-1995, we occasionally observed significant iron overloading in the liver. Liver tissue was examined by light and electron microscopy, and the results were analyzed by sex and age (7, 9, 11, 19, 31, 59, and 111 wk).
R, Masson, N O, Roome
openaire   +2 more sources

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

EFFECT OF ALPHA TOCOPHEROL ON CHRONIC STRESS INDUCED DERANGEMENTS INN NEUROPEPTIDEY ON SPRAGUE DAWLEY RATS

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the chronic stress induced decline in plasma Neuropeptide Y (NPY) level and protective effects of Alpha Tocopherol (AT) on maintenance of Neuropeptide Y level. Study Design: Quasi-experimental study.
Saadia Zainab, Umar Ali Khan, Ghulam Mustafa Lodhi, Munazza Asad   +3 more
doaj  

Antihyperlipidemic effect of Berberis orthobotrys in hyperlipidemic animal models

Bangladesh Journal of Pharmacology, 2014
The present study was undertaken to evaluate antihyperlipidemic effect of aqueous methanolic extract of Berberis orthobotrys in experimentally induced hyperlipidemic animal models. Atorvastatin was used as standard drug.
. Alamgeer, Aqsa Ghuffar, Taseer Ahmad, Muhammad Naveed Mushtaq   +3 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Splenic Hemangiosarcoma in a Young Sprague-Dawley Rat

Journal of Toxicologic Pathology, 2012
The present report describes a rare case of spontaneous hemangiosarcoma in a nine-week-old male Sprague-Dawley rat. At necropsy, multiple white nodules of various sizes were observed on and within the enlarged spleen and liver and were histopathologically determined to be composed of spindle- to oval-shaped cells that showed invasive growth without ...
Shiraki, Katsuhisa, Ono, Mihoko, Kajikawa, Satoru, Takeuchi, Ayano, Murakami, Yuichi, Oishi, Yuji, Matsumoto, Masahiro   +6 more
openaire   +3 more sources

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

The effect of 12 weeks of intermittent aerobic exercise on endothelin-1 concentration of plasma in adult rats

فصلنامه دانشگاه علوم پزشکی جهرم, 2013
Introduction: Endothelin is a vasoconstrictor which is released from the endothelium. The aim of the present study was to investigate the effect of intermittent aerobic exercise on the endothelin-1 concentration of plasma as an important indicator of ...
A Qassemian, M Koushki Jahromi
doaj   +2 more sources

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Allium vineale methanol extract attenuated oxidative stress and inflammation induced by doxorubicin in Sprague Dawley Rats

Scientific African, 2022
Doxorubicin-induced organ toxicities, through inflammation and oxidative stress, reduce its widespread use in the treatment of cancer. Thus, there is need for the development of less toxic and more effective plant-derived drugs and spice supplements to ...
Oluseyi A. Akinloye, Lateef A. Sulaimon, Abiodun O. Adewale, Toriola Mubaraq, Olanrewaju Salami, Odubiyi Abiola   +5 more
doaj   +1 more source