Results 151 to 160 of about 427,760 (358)

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

Case Reports of Situs Inversus Totalis and Dextrocardia in Sprague Dawley Rats

Veterinary Sciences, 2019
Situs inversus totalis is a condition where there is a transposition of all internal organs from their normal anatomical location. This infrequent and rare congenital condition has been described in several species of mammals. Dextorcardia is a series of
Reynaldo Oliva Hernández, Jordan D. Lewicky, Nya L. Fraleigh, Hoang-Thanh Le   +3 more
doaj   +1 more source

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

Advanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim, Hyeongseop Keum, Hassan Albadawi, Ismail Altinbasak, Furkan Yavuz, Erin H. Graf, Nitin Mishra, Rahmi Oklu   +7 more
wiley   +1 more source

Safety evaluation of CuminUP60® – A novel curcumin complex

Toxicology Reports, 2022
Curcuma longa L. is one of the most recognized Curcuma species (Sharifi-Rad et al., 2020 [3]). Curcumin, the primary polyphenolic compound found in turmeric has been used for a variety of purposes for centuries.
Margitta Dziwenka, Xin Li, Wenyu Li, Jiancheng Zong, Lei Zong, Shanglong Wang, Li Li, Zimin Liu, Zengliang Zhang, Mengyue Wang   +9 more
doaj  

Correlative Super‐Resolution Imaging of Cellular Nanopores Facilitated by Transparent Polymer Waveguide Chips

Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta, Jasmin Celine Schürstedt‐Seher, Anders Kokkvoll Engdahl, Wolfgang Hübner, Stefan Belle, Karolina Szafranska, Peter McCourt, Ralf Hellmann, Mark Schüttpelz, Thomas Huser   +9 more
wiley   +1 more source

Hypolipidemic Effect of Extra Virgin Olive Oil in Diabetic Rats

Journal of Rawalpindi Medical College, 2012
Background: To evaluate the effect of monounsaturated fatty acid and phenolic compounds enriched extra virgin olive oil on correction of dyslipidemia in diabetic rats.
Muhammad Javad Yousaf
doaj  

Effect of Low Selenium Diet on Glutathione Peroxidase 3 Concentration in Male Sprague-Dawley Rats’ Serum

Southeastern European Medical Journal, 2019
Aim: Determination of antioxidative enzyme glutathione peroxidase 3 (GPx3) serum concentrations after consumption of food which contains different concentrations of selenium (Se).
Nikolina Kolobaric (ex. Bilic-Dujmusic), Ana Stupin, Petar Šušnjara, Lidija Barić, Anita Matic   +4 more
doaj   +1 more source

Cold Plasma Generates a Localized Inflammatory Response and Promotes Muscle Repair

Advanced Therapeutics, EarlyView.
The immediate tissue response to plasma is a pro‐inflammatory response which is characterized by collagen clumping, innate immune cell infiltration, enhanced metabolic processes, and decreased apoptosis. The long‐term tissue response (4‐ and 14‐days) to plasma treatment is characterized by a decreased inflammatory response, decreased adipogenesis, and ...
Carly J. Smith, Amanda R. Watkins, Abigail A. Lucas, Arianna J. Moniodes, Conn Ritchie, Thomas P. Thompson, Thomas P. Schaer, Brendan F. Gilmore, Noreen J. Hickok, Theresa A. Freeman   +9 more
wiley   +1 more source

Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. [PDF]

, 2012
It has been reported that a diet enriched in fructose would present animal models used to emulate diabetes mellitus type 2 in human. This study aimed to examine the effect of high fructose induction on the blood glucose, C-reactive protein, interleukin-6,
Abd Mutalib, Mohd Sokhini, Khaza'ai, Huzwah, Zafershani, Aida   +2 more
core  

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source