Results 201 to 210 of about 448,712 (333)

Fructose consumption and metabolic hypertension in rats: a systematic review and meta-analysis. [PDF]

PeerJ
Vs A, Subramanian A, Rajendran K, Thamaraikani T, Kumarasamy V, Lian MS, Nordin RB, Sekar M, Subramaniyan V, Karnam M, Sackiriyas S, Wong LS.   +11 more
europepmc   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Contemporary in vivo rodent electroconvulsive therapy (ECT) models in translational depression research: a systematic review. [PDF]

Transl Psychiatry
Kokolakis E, Gottschalk MG, Kläffgen S, Deussing JM, Erhardt A, Pape JC, von Mücke-Heim IA.   +6 more
europepmc   +1 more source

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

Refined Surgical Protocol for the Insertion of Bioactive-coated Titanium Microscrews in the Rat Tibia. [PDF]

In Vivo
Vera-Becerra A, Valdivia-Gandur I, Acuña-Mardones P, Acevedo F, Veuthey C, Beltrán V.   +5 more
europepmc   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Acute and Subchronic Exposure to Hemp (<i>Cannabis sativa</i> L.) Leaf Oil: Impacts on Vital Organs in Sprague-Dawley Rats. [PDF]

Pharmaceuticals (Basel)
Maneesai P, Duangjinda M, Labjit C, Khamseekaew J, Potue P, Poasakate A, Pakdeechote P.   +6 more
europepmc   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Rat models for arterial calcification associated with chronic kidney disease: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Hense N, Stein M, Marx N, Kaesler N, Goettsch C.   +4 more
europepmc   +1 more source

Genotoxicity study of silver nanoparticles in bone marrow cells of Sprague-Dawley rats.

Food and Chemical Toxicology, 2015
A. Patlolla, Diahanna Hackett, P. Tchounwou   +2 more
semanticscholar   +1 more source