Results 181 to 190 of about 207,577 (260)

Protocol for In Utero Fetal-to-Fetal Kidney Transplantation in Rats. [PDF]

Bio Protoc
Morimoto K, Yamanaka S, Yokoo T.
europepmc   +1 more source

Translocator protein positron emission tomography as a biomarker for posttraumatic epilepsy and behavioral comorbidities following traumatic brain injury

Epilepsia, EarlyView.
Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar, Peravina Thergarajan, Juliana Silva, Emma Braine, Robert Brkljača, Pablo M. Casillas‐Espinosa, Stefanie Dedeurwaerdere, Mohammad Haskali, Usama Kamil, Terence J. O'Brien, Nigel C. Jones, David K. Wright, Bianca Jupp, Lucy Vivash, Idrish Ali   +14 more
wiley   +1 more source

Aging effects on emotionality, cognition and brain mononuclear cells in Sprague-Dawley rats of both sexes. [PDF]

NPJ Aging
Djuretić J, Ivanović J, Jezdić K, Todorović V, Bufan B, Santrač A, Aranđelović Ilić J.   +6 more
europepmc   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Discovery and characterization of canvuparatide, a once-weekly parathyroid hormone analog for the treatment of hypoparathyroidism. [PDF]

Mol Metab
Zhang F, Perez-Tilve D, Allen MR, Metzger CE, Dorato MA, Geiger MJ, DiMarchi RD.   +6 more
europepmc   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Oral-Systemic Links: A Narrative Review of the Role of Periodontitis in Alzheimer's Disease Development. [PDF]

Cureus
Spantidakis N, Zisis V, Charisi C, Fytros F, Poulopoulos K, Chontos T, Yiannouras A, Papadopoulos P, Katsagkolis A, Arsoudi V, Thomaidi ZM, Poulopoulos A, Diamanti S.   +12 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Neuroprotective Agents for Photoreceptor Rescue Following Experimental Retinal Detachment in Rodents: A Systematic Review. [PDF]

Invest Ophthalmol Vis Sci
Baroutis KG, Baroutis D, Ploumi I, Bantounou MA, Emfietzoglou M, Chatziralli I, Georgalas I, Theodossiadis P, Miller JW, Vavvas DG.   +9 more
europepmc   +1 more source