Results 151 to 160 of about 147,805 (240)

RETRACTION: Ameliorating Effect of <i>Malva neglecta</i> Wallr on Obesity and Diabetes in Wistar Rats: A Mechanistic Study. [PDF]

Biomed Res Int
International BR.
europepmc   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

Repeated Levonorgestrel Administration Impairs Cognitive Function via Glutamatergic Transmission and CaMKII-PKA-BDNF Signaling in the Hippocampus of Female Wistar Rats. [PDF]

J Exp Pharmacol
Abdulrahim HA, Omeiza NA, Akorede GJ, Iyapo O, Fatoki JO, Benneth BA, Oyewo EB, Oyewole AL, Alagbonsi AI, Adekunle AS.   +9 more
europepmc   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Regional differences in the distribution of melanocyte-containing hair bulbs in the skin of male albino rats. [PDF]

PLoS One
Numata N, Ozawa A, Sakaue M.
europepmc   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Heat exposure modulates redox balance and gonadal-related hormones in Wistar rats. [PDF]

JBRA Assist Reprod
Rotimi DE, Shalom AE, Adeyemi OS.
europepmc   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

RETRACTION: Ointment of <i>Brassica oleracea</i> var. <i>capitata</i> Matures the Extracellular Matrix in Skin Wounds of Wistar Rats. [PDF]

Evid Based Complement Alternat Med
And Alternative Medicine EC.
europepmc   +1 more source

Nanosilicates Enhanced Periodontal Angiogenesis by Regulating Microtubule Dynamic‐Mediated STAT3 Pathway

Cell Proliferation, EarlyView.
Nanosilicates triggered MAP4‐dependent microtubule remodelling via the ROS/MAPK pathway, shifting microtubules into a dynamic active state, which subsequently promoted activation of the STAT3 pathway, ultimately facilitating periodontal angiogenesis.
Lingling Shang, Yuhan Hu, Shaohua Ge
wiley   +1 more source