Results 181 to 190 of about 159,497 (267)

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

open access: yesJournal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee   +2 more
wiley   +1 more source

Smart Coatings Integrating Antimicrobial and Tissue‐Remodeling Functions for Implant Interfaces

open access: yesJournal of Periodontal Research, EarlyView.
Schematic illustration of a dental implant system showing inflammation around a non‐coated abutment (left) and a stimuli‐responsive coated abutment (right). Acidification associated with inflammation triggers degradation of the PMAA‐based coating, enabling controlled antibiotic release from the LbL system and combating bacterial infection.
Mariana Martins Guerreiro   +18 more
wiley   +1 more source

Pharmacological Modulation of Nrf2 Signaling Regulates Oxidative Stress, Inflammation, and Alveolar Bone Loss in Experimental Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Pharmacological activation of Nrf2 attenuated alveolar bone loss and protected periodontal tissues by reducing inflammation and oxidative stress, preserving collagen organization, and favoring bone homeostasis. Reversal of these effects by Nrf2 inhibition further supports Nrf2 signaling as a promising therapeutic target in periodontitis.
Vitória Bonan Costa   +8 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur   +3 more
wiley   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva   +2 more
wiley   +1 more source

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