Results 221 to 230 of about 342,681 (291)

Possible involvement of p60-S6K1 in accelerating RPS6 phosphorylation for rapid recovery from skeletal muscle disuse atrophy. [PDF]

Lab Anim Res
Inoue T, Kanazawa Y, Mizuguchi N, Maenishi O, Kimura M, Hagiyama M, Yoneshige A, Chikugo T, Itoh T, Satou T, Ito A.   +10 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Changes in the mucosal immunity induced by diets enriched with cocoa and hesperidin in intensively trained and exhausted rats. [PDF]

Sci Rep
Ruiz-Iglesias P, Pérez-Cano FJ, Rodríguez-Lagunas MJ, Castell M, Massot-Cladera M.   +4 more
europepmc   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

British Journal of Pharmacology, EarlyView.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy, Miles J. De Blasio, Owen L. Woodman, Pasquale Maffia, Hong Yong Peh, Cheng Xue Qin   +5 more
wiley   +1 more source

The Aphrodisiac and Androgenic Effects of Aqueous and Ethanol Extracts of <i>Tribulus cistoides</i> (Zygophyllaceae) on Nicotine-Induced Sexual Dysfunction in Male Wistar Rats. [PDF]

ScientificWorldJournal
Nsah KB, Mogho NMT, Fonkwo NS, Antoine KS.   +3 more
europepmc   +1 more source

Odanacatib Coating Supports Osseointegration of Implants: A Preclinical Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Introduction Odanacatib (ODN), a cathepsin K inhibitor, is a drug that reduces bone resorption while preserving bone formation. ODN was initially developed for the treatment of postmenopausal osteoporosis, but further development as a systemic medication has been discontinued.
Natália dos Santos Sanches, Caroline Liberato Marchiolli, Lara Cristina Cunha Cervantes, Maria Cristina Ruiz Voms Stein, Sara Alves Berton, Estéfany Lopes Lemes do Prado, Carina Kampleitner, Francisley Ávila Souza, Roberta Okamoto, Reinhard Gruber, Idelmo Rangel Garcia Júnior   +10 more
wiley   +1 more source

A comparative study of human ovarian tissue xenotransplantation in two different strains of rats. [PDF]

Animal Model Exp Med
Ayoubipour M, Eimani H, Fathi R, Ashtiani MK, Moinie A, Gerdkohi PG.   +5 more
europepmc   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Nutr
Luo D, Shang Z, He Q, Ke J, Xian Q, Dai S, Sun S, Xiong S.   +7 more
europepmc   +1 more source

Effects of methotrexate on Wnt/β‐catenin signaling and glial activation in temporomandibular joint arthritis in rats

European Journal of Oral Sciences, EarlyView.
Abstract Rheumatoid arthritis is a chronic autoimmune disease that can affect the temporomandibular joint (TMJ) and cause pain. Methotrexate is widely used to control disease progression, but its effects on pain mechanisms are not fully understood. This study evaluated the antinociceptive effects of methotrexate on pain behavior, Wnt/β‐catenin pathway ...
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Sofia Tavares Bessa, Anamaria Falcão Pereira, Paula Goes, Mariana Lima Vale, Delane Viana Gondim   +6 more
wiley   +1 more source