Results 71 to 80 of about 154,604 (268)

Effect of Moderate- and High-intensity Resistance Training on Some Serum Anabolic/Catabolic Osteokines in Old Male Wistar Rats

open access: yesMedical Laboratory Journal, 2021
Background and objectives: Bone-related osteokines play an important role in the response of bone metabolism to physical activity. The purpose of this study was to investigate effects of different intensities of resistance training on serum levels of ...
Mahnaz Shahbazi   +3 more
doaj  

Dopamine depletion in wistar rats with epilepsy

open access: yesBrazilian Journal of Biology
Abstract The dopamine content in cerebral structures has been related to neuronal excitability and several approaches have been used to study this phenomenon during seizure vulnerability period. In the present work, we describe the effects of dopamine depletion after the administration of 6-hidroxidopamine (6-OHDA) into the substantia nigra pars ...
E. M. Trindade-Filho   +25 more
openaire   +5 more sources

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

open access: yesChemFoodChem, EarlyView.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida   +7 more
wiley   +1 more source

The effect of the Tribulus terrestris extract on spermatogenesis in the rat [PDF]

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2012
According to our antecedents, in addition to other pharmacological properties, Tribulus terrestris increases sexual functioning and libido in men. Due to the fact that the benefits of herbal drugs should be approved clinically in the laboratory, the ...
Hojatolah Karimi Jashni   +2 more
doaj  

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner   +10 more
wiley   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén   +16 more
wiley   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira   +12 more
wiley   +1 more source

Avaliação da lesão isquêmica normotérmica do fígado: papel da oclusão do ducto biliar principal e da N-acetilcisteína

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Estudar o efeito da N-acetilcisteína (NAC) na isquemia hepática. MÉTODO: Trinta e oito ratos machos EPM-1 Wistar foram distribuídos em quatro grupos.
Susi Heliene Lauz Medeiros   +5 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference

open access: yesFrontiers in Psychiatry, 2019
Cocaine dependence is a psychiatric condition for which effective medications are still lacking. Published data indicate that an increase in nociceptin/orphanin FQ (N/OFQ) transmission by NOP receptor activation attenuates cocaine-induced place ...
Hongwu Li   +7 more
doaj   +1 more source

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