Results 161 to 170 of about 3,038,279 (306)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways. [PDF]

Int J Ophthalmol
Zhu D, Wu XY, Li LC.
europepmc   +1 more source

The Effect of Hypophysectomy on Immunity and Hypersensitivity in Rats with a Brief Description of the Operative Technic [PDF]

, 1939
Norman Molomut
openalex   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Rats! [PDF]

Nature Methods, 2010
openaire   +2 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Heqi San alleviates diabetic atherosclerosis and alters serum metabolic profiles in rats. [PDF]

BMC Cardiovasc Disord
Chu S, Wang H, Liu D, Zhao H, Li J, Liu X, Li H.   +6 more
europepmc   +1 more source

Cholesterol and liver vitamin A in male and female rats [PDF]

, 1957
B. Green, A A Horner, J. S. Lowe, R. A. Morton   +3 more
openalex   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Brown adipose tissue: a potential therapeutic target for preventing cardiovascular disease in metabolic disorders. [PDF]

Diabetol Metab Syndr
Egan Beňová T, Sýkora M, Ondreják Andelová K, Farkašová V, Lepáček M, Šoltésová Prnová M, Babál P, Janko D, Andelová N, Ferko M, Szeiffová Bačová B.   +10 more
europepmc   +1 more source