Results 171 to 180 of about 1,831,838 (319)

THE MECHANISM OF TRANSMISSION OF TRYPANOSOMA LEWISI FROM RAT TO RAT BY THE RAT FLEA [PDF]

BMJ, 1911
openaire   +2 more sources

Rat Behaviour [PDF]

Nature, 1953
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Surgical technical aspects of uniportal hybrid RATS and biportal pure RATS using a subcostal port. [PDF]

J Vis Surg
Kaneda H, Utsumi T, Murakawa T.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Application of a new high performance liquid chromatography method to the pharmacokinetics of dibudipine in rats [PDF]

Purpose: To develop a HPLC method for assay of dibudipine in biological fluids and to study its pharmacokinetics in the rat. Methods. HPLC: 2 μl (20 μg/ml) mebudipine as internal standard, 0.2 ml NaOH 1 M and 2 ml ethyl acetate were added to 0.2 ml of ...
محمودیان, مسعود, غیائی, سعید, کیهانفر, فریبرز, بهلولی, شهاب   +3 more
core  

Stable neuronal representations underlie cognitive resilience to Alzheimer's disease pathology. [PDF]

Alzheimers Dement
Chen K, Pineau E, Koletar M, Trevisiol A, He JS, Hill M, Goubran M, Sled J, McLaurin J, Stefanovic B.   +9 more
europepmc   +1 more source

Rat Surveys and Rat Proofing

American Journal of Public Health and the Nations Health, 1937
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain. [PDF]

Eur J Pain
Campos RMP, Conde L, Aguiar A, Sampaio L, de Melo Reis RA, Pimentel-Coelho PM.   +5 more
europepmc   +1 more source