Results 191 to 200 of about 1,985,228 (317)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Animal Models of Alzheimer's Disease Evaluated with [¹¹C]Pittsburg Compound B. [PDF]

Life (Basel)
Burgos-Puentes S, Avendaño-Estrada A, Sablón-Carrazana M, Ramírez-Hernández E, Granados-Juárez A, Ramírez-Rodríguez GB, Meraz-Ríos M, Martínez-Coria H, Ávila-Rodríguez MA.   +8 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Recombinant human thrombopoietin as a novel platelet-driven regulator accelerating hepatic regeneration in acute liver failure. [PDF]

Front Pharmacol
Shen Y, Han F, Wang T, Jing L, Luo Y, Ha F, Lu Y, Liang J.   +7 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Effect of Targeted Probiotics on Anesthesia-Induced Sleep Disturbances via Modulating the Gut Microbiome and Metabolites. [PDF]

Food Sci Nutr
Yang RZ, Lin S, Huang LT, Weng J, Liu QM, Chen HS, Ruan N, Zeng K.   +7 more
europepmc   +1 more source

Rosmarinic Acid as A Flavonoids Ameliorated Cytokines and Oxidative Stress Biomarkers in the Lung Lavage Fluid of Rats [PDF]

Vahideh Sadat Abbasnia, Mohsen Foadoddini, Mohammad Reza Khazdair   +2 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Effect of gentiopicroside on endogenous formaldehyde homocysteine-pathway related proteins in rats with non-alcoholic steatohepatitis. [PDF]

Front Pharmacol
Chen J, Zuo H, Jiao Y, Zhao H, Ma X, Xiao Y, Li X, Zhao W, Shi A, Chen W.   +9 more
europepmc   +1 more source

Efeito do óleo de copaíba associado à radiação no tratamento de carcinossarcoma induzido em ratos = Association between copaiba oil and radiotherapy on carcinossarcoma treatment in rats

, 2016
Phillipe Nogueira Barbosa Alencar
openalex   +1 more source