Results 71 to 80 of about 2,005,912 (260)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The aim of this study was to characterize the nitric oxide isoforms profile in rats’ nucleus tractus solitarii (NTS) and dorsal motor nucleus (DMN) of vagus nerve in arterial hypertension (AH) of various origin (essential (EAH) – rats of SHR line, and ...
M. V. Danukalo, O. V. Hancheva
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Pluronic F68 block polymer, a very potent suppressor of carcinogenesis in the colon of rats and mice [PDF]
, 2001 Polyethylene-glycol (PEG) is a strong inhibitor of colon cancer in rats, and the most potent suppressor of aberrant crypt foci. Nine PEG-like block copolymers were tested in rodents, after an azoxymethane injection.
Peiffer, Ginette +5 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EVIDENCE FOR FREE-RADICAL MEDIATED LIPID PEROXIDATION IN RATS AFTER COLD-IMMERSION STRESS [PDF]
, 2017 The role of cold immersion stress for the free-radical mediated lipid peroxidation in rat plasma and erythrocytes was studied. A model of cold-induced stress in rats was created.
Galunska, B. +3 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 2014 Boscia senegalensis has long been used as food, pesticide and medicine for the elimination of intestinal parasite from camel. The objective of this study was to evaluate the acute and sub acute toxicity (21 days) of Boscia senegalensis on the liver of ...
Albino Rats
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Effects of Barium Chloride on Metallothioneins Induction and Biochemical and Histomorphological Changes in the Kidney of Adult Female Rats [PDF]
Pharmaceutical and Biomedical ResearchBackground: Heavy metal exposure usually causes harmful effects on the environment and human health. Objectives: This study investigates the toxic effects of barium chloride (BaCl2) administered at graded doses to adult rats on kidney oxidative stress ...
Elwej Awatef +6 more
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