Results 1 to 10 of about 900 (95)

Development of an Immunochromatography Assay to Detect Marburg Virus and Ravn Virus [PDF]

Viruses, 2023
The recent outbreaks of Marburg virus disease (MVD) in Guinea, Ghana, Equatorial Guinea, and Tanzania, none of which had reported previous outbreaks, imply increasing risks of spillover of the causative viruses, Marburg virus (MARV) and Ravn virus (RAVV),
Katendi Changula, Masahiro Kajihara, Shino Muramatsu, Koji Hiraoka, Toru Yamaguchi, Yoko Yago, Daisuke Kato, Hiroko Miyamoto, Akina Mori-Kajihara, Asako Shigeno, Reiko Yoshida, Corey W. Henderson, Andrea Marzi, Ayato Takada   +13 more
doaj   +4 more sources

Characterization of Ravn virus viral shedding dynamics in experimentally infected Egyptian rousette bats (Rousettus aegypticus) [PDF]

Journal of Virology
Marburg virus (MARV) and Ravn virus (RAVV), the only two known members of the species Orthomarburgvirus marburgense (family Filoviridae), are causative agents of Marburg virus disease, a severe viral disease that typically emerges in sub-Saharan Africa ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +4 more sources

Divergent antibody recognition profiles are generated by protective mRNA vaccines against Marburg and Ravn viruses [PDF]

Nature Communications
The first-ever recent Marburg virus (MARV) outbreak in Tanzania and recent emergences in Rwanda, Ghana and Equatorial Guinea underscore the importance of therapeutic or vaccine development against the virus, for which none are approved.
Michelle Meyer, Bronwyn M. Gunn, Colette Pietzsch, Chandru Subramani, Kritika Kedarinath, Paula P. Villarreal, Matthew A. Hyde, Erica Ollmann Saphire, James E. Crowe, Galit Alter, Sunny Himansu, Andrea Carfi, Alexander Bukreyev   +12 more
doaj   +3 more sources

Revisiting Ravn virus as the lesser known orthomarburgvirus [PDF]

npj Viruses
Marburg virus (MARV) is a highly pathogenic zoonotic filovirus. The Orthomarburgvirus marburgense species includes MARV and Ravn virus (RAVV), which differs from MARV by 21% at the nucleotide level and 22% at the protein level.
Ivet A. Yordanova, Joseph B. Prescott
doaj   +2 more sources

Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Rousettus aegyptiacus) [PDF]

Journal of Virology
Viral coinfections and their impact on long-term immunity represent an understudied area in disease ecology and infectious disease research. Coinfections can influence the host’s susceptibility to future infections, alter host and pathogen population ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +2 more sources

Immunoinformatics-guided design of a universal chimeric multi-epitope subunit vaccine against Marburg virus disease and Ravn virus co-infection [PDF]

Scientific Reports
Marburg Virus Disease (MVD) is a life-threatening hemorrhagic fever, caused by two viruses-Marburg virus (MARV) and Ravn virus (RAVV)-that belong to the family Filoviridae.
Sardar Ali, Abdullah Shah, Sikandar Khan, Muhammad Suleman, Ziaul Islam, Muhammad Tahir Aleem   +5 more
doaj   +2 more sources

Serologic evidence of orthomarburgviruses and an orthoebolavirus in frugivorous Malagasy bats [PDF]

One Health Outlook
Recent outbreaks of Marburg virus disease in regions of sub-Saharan Africa without prior record such as Ghana, Tanzania, Equatorial Guinea, and Rwanda challenge the current understanding of areas at-risk for filovirus spillover.
Marana S. Rekedal, Emily Cornelius Ruhs, Hafaliana Christian Ranaivoson, Neil Mittal, Spencer L. Sterling, Gwenddolen Kettenburg, Angelo Andrianiaina, Santino Andry, Lianying Yan, Axel T. Lehrer, Jean-Michel Héraud, Vincent Lacoste, Philippe Dussart, Cara E. Brook, Eric D. Laing   +14 more
doaj   +2 more sources

Discovery of potent cross-neutralizing antibodies against Marburg and Ravn viruses with therapeutic potential [PDF]

npj Viruses
Marburg virus (MARV) and Ravn virus (RAVV) are highly pathogenic filoviruses that cause Marburg virus disease (MVD), for which no approved treatment currently exists.
Takeshi Saito, Hiroko Miyamoto, Manabu Igarashi, Asuka Nanbo, Risa Hayashi, Ruchi Paroha, Gavriella Siman-Tov, Kirsten Littlefield, Akina Mori-Kajihara, Christine Click, Wakako Furuyama, Slobodan Paessler, Junki Maruyama, Ayato Takada   +13 more
doaj   +2 more sources

Genomic Evolution and Phylodynamics of the Species Orthomarburgvirus marburgense (Marburg and Ravn Viruses) to Understand Viral Adaptation and Marburg Virus Disease’s Transmission Dynamics [PDF]

Pathogens
In this review, we investigated the genetic diversity and evolutionary dynamics of the Orthomarburgvirus marburgense species that includes both Marburg virus (MARV) and Ravn virus (RAVV).
Claude Mambo Muvunyi, Nouh Saad Mohamed, Emmanuel Edwar Siddig, Ayman Ahmed   +3 more
doaj   +2 more sources

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health. [PDF]

Microb Biotechnol
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Brüssow H.
europepmc   +2 more sources